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The triterpenoid alpha, beta-amyrin prevents the impaired aortic vascular react...

Santos, Flávia Almeida; Batista-Lima, Francisco José; Nunes, Paulo Iury Gomes; Viana, Ana Flávia Seraine Custódio

To characterize the pro tective effects of the triterpenoid mixture alpha, beta-amyrin (AMY, 20 mg/kg, during 15 days) on the reactivity of isolated aorta of high- fat diet (HFD)-induced obese mice. Male Swiss mice were fed with HFD or normal diet (ND) for 15 weeks. Contractions of thoracic aorta in response to KCl or phen- ylephrine (PHE) and relaxation by acetylcholine (ACh) or sodium nitroprusside (SNP) were...

Date: 2017   |   Origin: Oasisbr
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