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Hyperoside Supplementation in Preservation Media Surpasses Vitamin C Protection...

Moreira, MV; Pereira, SC; Guerra-Carvalho, B; Carrageta, DF; Pinto, S; Barros, A; Silva, BM; Oliveira, PF; Alves, MG

Background/Aims: Oxidative Stress (OS) is reported as one of the main causes of male infertility. Infertile couples often resort to assisted reproductive technology (ART) to achieve parenthood. However, preparation for ART protocols increases the exposer of gametes to OS. Thus, it is crucial to find suitable preservation media that can counteract the OS-induced damages in spermatozoa. In this work, we tested an...


Amphibians on the hotspot: Molecular biology and conservation in the South Amer...

Amaral, CRL; Chaves, ACS; Borges, VNT; Pereira, F; Silva, BM; Silva, DA; Amorim, A; Carvalho, EF; Rocha, CFD

Amphibians are the focus of a recent debate and public attention owing to the global decline in their populations worldwide. Amphibians are one of the most threatened and poorly known groups of vertebrates in several geographic areas, even though they play a central role in their own ecosystems. At different levels, amphibians make their contribution to proper ecosystem functioning. They act as regulators of th...


SIRT1 and mTOR interplay in bladder cancer: a potential therapeutic target

Oliveira, P; Silva, AM; Tavares da Silva, E; Jarak, I; Abrantes, M; Botelho, MF; Figueiredo, A; Silva, BM; Pereira, JA; Oliveira, PF; Alves, MG


Surgical Treatment of Rotator Cuff Tears After 65 Years of Age: A Systematic Re...

Silva, BM; Cartucho, A; Sarmento, M; Moura, N

INTRODUCTION: The objective of this study was to analyze current evidence regarding surgical management of rotator cuff tears in patients of 65 years of age and above. Our hypothesis was that surgical repair of rotator cuff tears, in patients older than 65 years, conveys good outcome scores. We have not found a similar systematic review in current literature. MATERIAL AND METHODS: Medline®, PubMed, Scopus, and ...

Date: 2017   |   Origin: Saúde - CUF

HFE gene polymorphisms and severity in Portuguese patients with multiple sclerosis

Bettencourt, A; Silva, AM; Santos, E; Gomes, S; Mendonça, D; Costa, PP; Faustino, Paula; Silva, BM

Background: High iron concentrations have been reported in oligodendrocytes, myelin and macrophages in multiple sclerosis (MS) lesions. It has been proposed that HFE gene polymorphisms could have a role in MS. Methods: The C282Y and H63D HFE variants frequencies were determined in 373 patients with MS and compared with a normal population. Results: No significant association was found between HFE polymorphisms ...


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