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Combined exercise hinders the progression of pulmonary and right heart harmful ...

Leite, Luciano Bernardes; Soares, Leôncio Lopes; Portes, Alexandre Martins Oliveira; Silva, Bruna Aparecida Fonseca da; Dias, Taís Rodrigues

The aim of this study was to test whether combined physical exercise training of moderate intensity executed during the devel- opment of monocrotaline (MCT)-induced pulmonary arterial hypertension (PAH) hinders the progression of pulmonary and right heart harmful functional and structural remodeling in rats. Wistar rats were injected with MCT (60 mg/kg) and after 24 h were exposed to a combined exercise trainin...

Date: 2025   |   Origin: Biblioteca Digital do IPB

Resistance Training Before Hyperalgesia Induction Promotes Analgesic Effects Th...

Chiapeta, Andrês Valente; Oliveira, Leandro Licursi; Leite, Luciano Bernardes; Silva, Bruna Aparecida Fonseca da; Costa, Sebastião Felipe Ferreira

Fibromyalgia is a chronic syndrome characterized by widespread pain and complex pathophysiology, requiring new therapeutic approaches. This study aims to investigate the effects of resistance training (RT) before hyperalgesia induction on pain sensitivity, IL-6 and IL-10 expression in skeletal muscle, and thalamic serotonin levels in a fibromyalgia (FM)-like rat model. Methods: Wistar female rats aged 12 months...

Date: 2025   |   Origin: Biblioteca Digital do IPB

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