3 documents found, page 1 of 1
Evaluación de la citotoxicidad, genotoxicidad y toxicidad subcrónica de diéster...
Canabrava, Natália do Vale; Silva, Jose Ytalo Gomes da; Silva, Bruno Bezerra da; Holanda, Marcelo Oliveira; Lima, Carla Laine SilvaP-methoxycinnamic diesters from carnauba wax powder (PCO - C) – cinnamic acid derivate – have been associated with new properties such as hypolipidemic, hypocholesterolemic and hypoglycaemic effects in mice. The present study aimed to investigate the safety profile of PCO - C by evaluating the subchronic oral toxicity, genotoxicity and mutagenicity using in vivo experimental models. Therefore, for the present r...
p-Methoxycinnamic acid diesters lower dyslipidemia, liver oxidative stress and ...
Paim, Raquel Teixeira Terceiro; Rodrigues, Paula Salmito Alves; Silva, José Ytalo Gomes da; Paula Junior, Valdir Ferreira de; Silva, Bruno Bezerra daThe pursuit of cholesterol lowering natural products with less side e ects is needed for controlling dyslipidemia and reducing the increasing toll of cardiovascular diseases that are associated with morbidity and mortality worldwide. The present study aimed at the examining e ects of p-methoxycinnamic acid diesters (PCO-C) from carnauba (Copernicia prunifera)-derived wax on cytotoxic, genotoxic responses in vit...
Nutriproteomics for obesity research
Brito, Fernando César Rodrigues; Lima Neto, Abelardo Barbosa Moreira; Silva, Bruno Bezerra da; Cunha, Luana Mara Silva de Castro Pacheco daThis study aimed to review findings of scientific articles which the use of proteomic tools made it possible to characterize the metabolic profile of obese individuals. We searched the electronic databases: Scielo, PubMed, Lilacs and capes. The time period was defined as 10 years, having as main keywords: proteomics, proteome, obesity, biomarkers. The use of serum proteomic techniques proposed prognostic marker...