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Temporal oral microbiome changes with brushing in children with cleft lip and p...

Rodrigues, Rita; Chung, Ana P.; Mortensen, Martin S.; Fernandes, Maria H.; Monteiro, António B.; Furfuro, Rowney; Silva, Cátia C.; Manso, Maria C.

This cohort study aimed to characterize the oral microbiome of children with CLP, from two different age groups, and evaluate the effect of supervised or unsupervised toothbrushing on the microbiome of the cleft over time. Swab samples were collected from the cleft area at three different time points (A; no brushing, B; after 15 days and C; after 30 days) and were analyzed using next-generation sequencing to de...


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