125 documents found, page 1 of 13
Development and validation of a Portuguese psychologist's empathy scale: A pilo...
Cruz, Márcia; Grilo, Ana; Custódio, Susana; Dores, Artemisa R.; Silva, Carina; Alves, Paulo; Dores, ArtemisaThe systematic assessment of empathy is essential for identifying psychologists' competencies and developmental needs, ultimately contributing to more effective clinical practice. Given the multidimensional nature of empathy, comprehensive evaluation requires consideration of its cognitive, affective, and behavioural dimensions. How ever, no existing instrument is specifically validated to assess psychologists'...
Development and validation of a Portuguese psychologist's empathy scale: a pilo...
Cruz, Márcia; Grilo, Ana; Custódio, Susana; Dores, Artemisa R.; Silva, Carina; Alves, PauloThe systematic assessment of empathy is essential for identifying psychologists' competencies and developmental needs, ultimately contributing to more effective clinical practice. Given the multidimensional nature of empathy, comprehensive evaluation requires consideration of its cognitive, affective, and behavioural dimensions. However, no existing instrument is specifically validated to assess psychologists' ...
Epigenetic Signatures of DNMTs and Retinal Structural Changes in Age-Related Ma...
Afonso, Ana; Nobre, Diana; Lino, Leonor; Ribeiro, Edna; Pereira, Bruno; Ginete, Catarina; Silva, Carina; Brito, Miguel; Camacho, Pedro; Pereira, BrunoIntroduction: Age-related macular degeneration (AMD) is one of the leading causes of irreversible visual loss in the elderly. Identifying effective biomarkers is essential due to the limited therapeutic options in the early stages. Epigenetic alterations, such as DNA methyltransferase (DNMT) expression, have been implicated in AMD pathogenesis; however, their association with structural changes in the choroid a...
Development and validation of a Portuguese psychologist's empathy scale: A pilo...
Cruz, Márcia; Grilo, Ana; Custódio, Susana; Dores, Artemisa R.; Silva, Carina; Alves, PauloThe systematic assessment of empathy is essential for identifying psychologists' competencies and developmental needs, ultimately contributing to more effective clinical practice. Given the multidimensional nature of empathy, comprehensive evaluation requires consideration of its cognitive, affective, and behavioural dimensions. However, no existing instrument is specifically validated to assess psychologists' ...
Portuguese cross-cultural adaptation and validation of the hospital survey on p...
Freitas, Elsa; Silva, Carina; Eiras , MargaridaBackground: As patient safety continues to be a global priority, it is crucial to emphasize the assessment and development of Patient Safety Culture [PSC] to advance healthcare quality and safety initiatives worldwide. This study focused on the assessment of PSC in Portuguese hospitals, specifically through the translation and cultural adaptation of the Hospital Survey on Patient Safety Culture 2.0 [HSOPSC 2.0]...
Writing difficulties and functional vision in elementary school children: dysor...
Poças, Ilda Maria; Silva, Carina; Besidovska, Anzhelika; Rocha, Marlene; Valimamade, Nilsa; Mourato, Patrícia; Martins, SaraIntroduction – Vision is an important means of physical, behavioural, and cognitive development in children, having great relevance in the learning process. Aim of the study – To characterize the visual function anomalies that contribute to writing difficulties in 3rd and 4th year of schooling. Methods – Quantitative, descriptive, observational, cross-sectional, and correlational study. Sample of 232 students, ...
DNA methyltransferase expression (DNMT1, DNMT3a, and DNMT3b) as a potential bio...
Camacho, Pedro; Ribeiro, Edna; Pereira, Bruno; Nascimento, João; Rosa, Paulo Caldeira; Henriques, José; Barrão, Sandra; Sadio, Silvia; Quendera, BrunoBackground/Objectives: Age-related macular degeneration (AMD) is a global cause of vision loss, with limited therapeutic options highlighting the need for effective biomarkers. This study aimed to characterize plasma DNA methyltransferase expression (DNMT1, DNMT3A, and DNMT3B) in AMD patients and explore divergent expression patterns across different stages of AMD. Methods: Thirty-eight AMD patients were prospe...
Genetic modifiers of sickle cell anemia severity in an Angolan cohort
Ginete, Catarina; Delgadinho, Mariana; Santos, Brígida; Miranda, Armandina; Silva, Carina; Guerreiro, Paulo; Chimusa, Emile R.; Brito, MiguelIntroduction: Sickle Cell Anemia (SCA) is an inherited disease caused by a single nucleotide substitution in the HBB gene, that encodes for the B-globin subunit of hemoglobin. Although patients’ phenotypes are very heterogeneous, in terms of severity and life span, patients homozygous for this mutation usually exhibit chronic hemolytic anemia, report frequent and severe painful crises, and present extensive org...
DNA Methyltransferase Expression (DNMT1, DNMT3a, and DNMT3b) as a Potential Bio...
Camacho, Pedro; Ribeiro, Edna; Pereira, Bruno; Nascimento, João; Caldeira Rosa, Paulo; Henriques, José; Barrão, Sandra; Sadio, Silvia; Quendera, BrunoAge-related macular degeneration (AMD) is a global cause of vision loss, with limited therapeutic options highlighting the need for effective biomarkers. This study aimed to characterize plasma DNA methyltransferase expression (, , and ) in AMD patients and explore divergent expression patterns across different stages of AMD. : Thirty-eight AMD patients were prospectively enrolled and stratified by disease seve...
Modulação da expressão de microRNAs em células humanas K562 induzida por extrat...
Edna; Ribeiro, Edna; Canteiro , Beatriz; Ginete , Catarina; Gomes, Mário; Brito, Miguel; Gomes, Anita; Silva, CarinaIntrodução – As hemoglobinopatias constituem um dos grupos de doenças monogénicas mais prevalentes a nível mundial. Atualmente, um dos tratamentos disponíveis consiste na indução farmacológica da hemoglobina fetal (HbF) através de vários compostos químicos, sendo o mais comum a hidroxiureia (HU). Contudo, o seu custo elevado em países subdesenvolvidos e o seu perfil de segurança limitam a utilização deste compo...