2 documents found, page 1 of 1
Synthesis, in vitro and in vivo anti-Trypanosoma cruzi and toxicological activi...
Almeida, Tamires Cunha; Ribeiro, Luis Henrique Gonzaga; Santos, Luiza Braga Ferreira dos; Silva, Cleiton Moreira da; Branquinho, Renata TupinambáChagas disease is a major health problem not only in Latin America but also in Europe and North America due to the spread of this disease into nonendemic areas. In terms of global burden, this major tropical infection is considered to be one of the most neglected diseases, and there are currently only two available chemotherapies: benznidazole and nifurtimox. Unfortunately, although these chemotherapies are ben...
Síntese e fitotoxicidade de benzopironas análogas ao alternariol
Silva, Cleiton Moreira daCoordenação de Aperfeiçoamento de Pessoal de Nível Superior; Fungi of the genus Alternaria are known to cause foliar injury in a variety of plants. Studies show that alternariol, a secondary metabolite produced by these microorganisms may be directly related to its phytotoxicity, including on weeds. In this context, this work aimed to synthesize several alternariol analogues as well as evaluate the phytotoxic a...