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Joint model for zero-inflated data combining fishery-dependent and fishery-inde...

Silva, Daniela; Menezes, Raquel; Araújo, Gonçalo; Rosa, Renato; Moreno, Ana; Silva, Alexandra; Garrido, Susana

Accurately identifying spatial patterns of species distribution is crucial for scientific insight and societal benefit, aiding our understanding of species fluctuations. The increasing quantity and quality of ecological datasets present heightened statistical challenges, complicating spatial species dynamics comprehension. Addressing the complex task of integrating multiple data sources to enhance spatial fish ...


Form Follows Life: Reinventing cities. Non Architecture publishing

Bina, Olivia; Silva, Daniela; Fokdal, Josefine; de Stefano, Luca

The aim of this report is to present and discuss the results of the Non Architecture Competition: “Form Follows Life: Reinventing Cities”. Following Non Architecture’s engagement with the potentialities, and urgencies, surrounding cities and “nature” over the last few years, we came together to curate a competition that sought to challenge as much as possible current paradigms shaping ideas about what is “urban...


Joint model for zero-inflated data combining fishery-dependent and fishery-inde...

Silva, Daniela; Menezes, Raquel; Araújo, Gonçalo; Rosa, Renato; Moreno, Ana; Silva, Alexandra; Garrido, Susana

Accurately identifying spatial patterns of species distribution is crucial for scientific insight and societal benefit, aiding our understanding of species fluctuations. The increasing quantity and quality of ecological datasets present heightened statistical challenges, complicating spatial species dynamics comprehension. Addressing the complex task of integrating multiple data sources to enhance spatial fish ...


Insight into the efficiency of microalgae’ lipidic extracts as photosensitizers...

Mendonça, Inês; Silva, Daniela; Conde, Tiago; Maurício, Tatiana; Cardoso, Helena; Pereira, Hugo; Bartolomeu, Maria; Vieira, Cátia; Domingues, M. Rosário

Antibacterial resistance causes around 1.27 million deaths annually around the globe and has been recognized as a top 3 priority health threat. Antimicrobial photodynamic therapy (aPDT) is considered a promising alternative to conventional antibiotic treatments. Algal lipid extracts have shown antibacterial effects when used as photosensitizers (PSs) in aPDT. In this work we assessed the photodynamic efficiency...


A One pathology multicentre Portuguese approach to thyroid tumours of dogs and ...

Gaspar, Tiago; Borges, Inês; Canberk, Sule; Monteiro, Alexandra; Catarino, José; Pinto, Mafalda; Teixeira, Elisabete; Canadas-Sousa, Ana; Branco, Sandra

Thyroid tumours are the most common endocrine tumours of dogs and cats. Feline thyroid tumours are essentially functional adenomas curable with thyroidectomy, whereas most canine thyroid tumours are non-functional carcinomas either unresectable or recurrent within two years in up 50%. The oncobiology of these tumours remains unclear, but investigating this aspect could contribute to the development of targeted ...


Preventing Clostridioides difficile infection by using an immobilized bile salt...

Silva, Daniela

"The anaerobe Clostridioides difficile is a leading cause of healthcare-associated infections. C. difficile infection occurs after faecal-oral transmission of spores that germinate in the gut in response to certain bile salts. Commensal microbiota prevents spore germination by modulating the bile acid pool. Therefore, spore germination, toxin production and disease only occurs under dysbiosis, normally caused b...


Tumor-infiltrating T cells in skin basal cell carcinomas and squamous cell carc...

Cunha, Daniela; Neves, Marco; Silva, Daniela; Silvestre, Ana Rita; Borralho, Paula; Arrobas, Fernando; Ribot, Julie; Ferreira, Fernando; Moita, Luís F.

Basal cell carcinomas (BCCs) and squamous cell carcinomas (SCCs) are high-incidence, non-melanoma skin cancers (NMSCs). The success of immune-targeted therapies in advanced NMSCs led us to anticipate that NMSCs harbored significant populations of tumor-infiltrating lymphocytes with potential anti-tumor activity. The main aim of this study was to characterize T cells infiltrating NMSCs. Flow cytometry and immuno...


Insight into the efficiency of microalgae’ lipidic extracts as photosensitizers...

Mendonça, Inês; Silva, Daniela; Conde, Tiago; Maurício, Tatiana; Cardoso, Helena; Pereira, Hugo; Bartolomeu, Maria; Vieira, Cátia; Domingues, M. Rosário

Antibacterial resistance causes around 1.27 million deaths annually around the globe and has been recognized as a top 3 priority health threat. Antimicrobial photodynamic therapy (aPDT) is considered a promising alternative to conventional antibiotic treatments. Algal lipid extracts have shown antibacterial effects when used as photosensitizers (PSs) in aPDT. In this work we assessed the photodynamic efficiency...


A One-Year Systematic Study to Assess the Microbiological Profile in Oysters fr...

Rodrigues, Inês C; Santos-Ferreira, Nânci; Silva, Daniela; da Silva, Carla Chiquelho; Inácio, Ângela S.; Nascimento, Maria São José

As filter-feeding animals farmed in water bodies exposed to anthropogenic influences, oysters can be both useful bioremediators and high-risk foodstuffs, considering that they are typically consumed raw. Understanding the dynamic of bacterial and viral load in Pacific oyster (Crassostrea gigas) tissues, hemolymph, outer shell surface biofilm, and farming water is therefore of great importance for microbiologica...


Adapting the sampling design of research surveys to improve the biomass estimat...

Silva, Daniela; Menezes, Raquel; Serra-Pereira, Bárbara; Azevedo, Manuela; Figueiredo, Ivone

Research surveys are important to evaluate the spatial distribution of fishery re sources and to monitor their abundance. However, the underlying sampling is usually conceived with the focus on specific species and an efficient design may reconcile this objective with the collection of non-target species data. This study evaluates the adequacy of different sampling designs for the IPMA bottom trawl survey condu...


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