69 documents found, page 1 of 7
Insight into the efficiency of microalgae’ lipidic extracts as photosensitizers...
Mendonça, Inês; Silva, Daniela; Conde, Tiago; Maurício, Tatiana; Cardoso, Helena; Pereira, Hugo; Bartolomeu, Maria; Vieira, Cátia; Domingues, M. RosárioAntibacterial resistance causes around 1.27 million deaths annually around the globe and has been recognized as a top 3 priority health threat. Antimicrobial photodynamic therapy (aPDT) is considered a promising alternative to conventional antibiotic treatments. Algal lipid extracts have shown antibacterial effects when used as photosensitizers (PSs) in aPDT. In this work we assessed the photodynamic efficiency...
Insight into the efficiency of microalgae’ lipidic extracts as photosensitizers...
Mendonça, Inês; Silva, Daniela; Conde, Tiago; Maurício, Tatiana; Cardoso, Helena; Pereira, Hugo; Bartolomeu, Maria; Vieira, Cátia; Domingues, M. RosárioAntibacterial resistance causes around 1.27 million deaths annually around the globe and has been recognized as a top 3 priority health threat. Antimicrobial photodynamic therapy (aPDT) is considered a promising alternative to conventional antibiotic treatments. Algal lipid extracts have shown antibacterial effects when used as photosensitizers (PSs) in aPDT. In this work we assessed the photodynamic efficiency...
Preventing Clostridioides difficile infection by using an immobilized bile salt...
Silva, Daniela"The anaerobe Clostridioides difficile is a leading cause of healthcare-associated infections. C. difficile infection occurs after faecal-oral transmission of spores that germinate in the gut in response to certain bile salts. Commensal microbiota prevents spore germination by modulating the bile acid pool. Therefore, spore germination, toxin production and disease only occurs under dysbiosis, normally caused b...
Tumor-infiltrating T cells in skin basal cell carcinomas and squamous cell carc...
Cunha, Daniela; Neves, Marco; Silva, Daniela; Silvestre, Ana Rita; Borralho, Paula; Arrobas, Fernando; Ribot, Julie; Ferreira, Fernando; Moita, Luís F.© 2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).; Basal cell carcinomas (BCCs) and squamous cell carcinomas (SCCs) are high-incidence, non-melanoma skin cancers (NMSCs). The success of immune-targeted therapies in advanced ...
Adapting the sampling design of research surveys to improve the biomass estimat...
Silva, Daniela; Menezes, Raquel; Serra-Pereira, Bárbara; Azevedo, Manuela; Figueiredo, IvoneResearch surveys are important to evaluate the spatial distribution of fishery re sources and to monitor their abundance. However, the underlying sampling is usually conceived with the focus on specific species and an efficient design may reconcile this objective with the collection of non-target species data. This study evaluates the adequacy of different sampling designs for the IPMA bottom trawl survey condu...
Effect of phage vB_EcoM_FJ1 on the reduction of ETEC O9:H9 infection in a neona...
Ferreira, Alice Maria Fernandes; Silva, Daniela; Almeida, Carina; Rodrigues, Maria Elisa Costa; Silva, Sónia Carina; Castro, Joana Isabel ReisEnterotoxigenic Escherichia coli (ETEC) colonizes the intestine of young pigs causing severe diarrhoea and consequently bringing high production costs. The rise of antibiotic selective pressure together with ongoing limitations on their use, demands new strategies to tackle this pathology. The pertinence of using bacteriophages as an alternative is being explored, and in this work, the efficacy of phage vB\_Eco...
Interlaboratory validation of a multiplex qPCR method for the detection of list...
Azinheiro, Sarah; Rodríguez-López, Pedro; Lozano-León, Antonio; Guedes, Hugo; Regal, Patricia; Franco, Carlos M.; Cepeda, AlbertoListeria monocytogenes is a major foodborne pathogen which mainly infects susceptible individuals through the consumption of contaminated foods. To this end, ready-to-eat (RTE) food products are of particular concern as this microorganism is widely distributed, can survive, and even grow, under adverse conditions, and thus must be carefully controlled. In the present study, an interlaboratory ring trial was org...
A One-Year Systematic Study to Assess the Microbiological Profile in Oysters fr...
Rodrigues, Inês C; Santos-Ferreira, Nânci; Silva, Daniela; da Silva, Carla Chiquelho; Inácio, Ângela S.; Nascimento, Maria São JoséAs filter-feeding animals farmed in water bodies exposed to anthropogenic influences, oysters can be both useful bioremediators and high-risk foodstuffs, considering that they are typically consumed raw. Understanding the dynamic of bacterial and viral load in Pacific oyster (Crassostrea gigas) tissues, hemolymph, outer shell surface biofilm, and farming water is therefore of great importance for microbiologica...
Validation of a suggested pre-operative protocol for the prevention of traumati...
Silva, Daniela; Miranda, Rita; Ferreira, Inês; Braga, A. C.; Mourão, Joana; Pina-Vaz, IreneThe aim of this study was to develop a protocol for oral pre-operative registration and dental risk assessment by the anaesthesiologist, determining its reliability through the inter-observer agreement between a senior dental student and an internal physician specializing in anaesthesiology. A convenience sample consisting of 35 patients was selected. These were observed during the anaesthesiology consultation,...
Environmental effects on the spatiotemporal variability of sardine distribution...
Silva, Daniela; Menezes, Raquel; Moreno, Ana; Teles-Machado, Ana; Garrido, SusanaScientific tools capable of identifying distribution patterns of species are important as they contribute to improve knowledge about biodiversity and species dynamics. The present study aims to estimate the spatiotemporal distribution of sardine (Sardina pilchardus, Walbaum 1792) in the Portuguese continental waters, relating the spatiotemporal variability of biomass index with the environmental conditions. Aco...