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Fisetin derivatives exhibit enhanced anti-inflammatory activity and modulation ...

Silva, Daniela Correia da; Jervis, Peter John; Martins, J. A. R.; Valentão, Patrícia; Ferreira, Paula M. T.; Pereira, David M.

Fisetin (FST) is a dietary flavonol that is known to possess multiple relevant bioactivities, raising the question of its potential health benefits and even its use in novel pharmacological approaches. To attain this prospect, some limitations to this molecule, namely its poor bioavailability and solubility, must be addressed. Inflammation and endoplasmic reticulum (ER) stress are often hand in hand in the cont...


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