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PVA-Based Hydrogels Loaded with Diclofenac for Cartilage Replacement

Branco, Ana C.; Oliveira, Andreia S.; Monteiro, Inês; Nolasco, Pedro; Silva, Diana C.; Figueiredo-Pina, Célio; Colaço, Rogério; Serro, Ana P.

Polyvinyl alcohol (PVA) hydrogels have been widely studied for cartilage replacement due to their biocompatibility, chemical stability, and ability to be modified such that they approximate natural tissue behavior. Additionally, they may also be used with advantages as local drug delivery systems. However, their properties are not yet the most adequate for such applications. This work aimed to develop new PVA-b...


PVA-based hydrogels loaded with diclofenac for cartilage replacement

Branco, Ana C.; Oliveira, Andreia S.; Monteiro, Inês; Nolasco, Pedro; Silva, Diana C.; Figueiredo-Pina, Célio G.; Colaço, Rogério; Serro, Ana P.

Polyvinyl alcohol (PVA) hydrogels have been widely studied for cartilage replacement due to their biocompatibility, chemical stability, and ability to be modified such that they approximate natural tissue behavior. Additionally, they may also be used with advantages as local drug delivery systems. However, their properties are not yet the most adequate for such applications. This work aimed to develop new PVA-b...


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