4 documents found, page 1 of 1
Novel Insights in the Management of Vernal Keratoconjunctivitis (VKC): European...
Dahlmann-Noor, A; Bonini, S; Bremond-Gignac, D; Heegaard, S; Leonardi, S; Montero, J; Silva, EDIntroduction: Vernal keratoconjunctivitis (VKC) is a rare, severe allergic ocular disease, typically occurring in children and adolescents, that can have a significant impact on quality of life and lead to visual impairment. Long-term treatment may be necessary to tackle chronic inflammation and topical corticosteroid dependency must be minimised due to the risk of complications. There is a need for unified cli...
Neonatal Apex Resection Triggers Cardiomyocyte Proliferation, Neovascularizatio...
Sampaio-Pinto, V; Rodrigues, SC; Laundos, TL; Silva, ED; Vasques-Nóvoa, F; Silva, AC; Cerqueira, R; Resende, TP; Pianca, N; Leite-Moreira, A; D'Uva, GSo far, opposing outcomes have been reported following neonatal apex resection in mice, questioning the validity of this injury model to investigate regenerative mechanisms. We performed a systematic evaluation, up to 180 days after surgery, of the pathophysiological events activated upon apex resection. In response to cardiac injury, we observed increased cardiomyocyte proliferation in remote and apex regions,...
Novel de novo FOXC1 nonsense mutation in an Axenfeld-Rieger syndrome patient
Carmona, S; da Luz Freitas, MG; Froufe, H; Simões, MJ; Sampaio, MJ; Silva, ED; Egas, C
Novel de novo FOXC1 nonsense mutation in an Axenfeld-Rieger syndrome patient
Carmona, S; da Luz Freitas, M; Froufe, H; Simões, MJ; Sampaio, MJ; Silva, ED; Egas, C