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Human Papilomavirus infection and Ki-67 expression in Penile Cancer: Do they re...

Mendes, Fernando; Vilela, Marisa; Silva, Edgar Tavares; Quaresma, Vasco; Almeida, Rui; Silva, Maria Fátima; Teixeira, Paulo; Martins, Diana

Introduction: Squamous cell carcinoma (SCC) of the penis is a rare but devastating neoplasm for the patient. Human Papillomavirus (HPV) infection can induce penile carcinogenesis and may contribute to 30 to 50% of penile cancer (PeCa) cases. The overexpression of P16INK4a can be used as a surrogate marker for active HPV infections, although the correlation between HPV infection in PeCa still is controversial. K...


Histological scores and tumor size on stage II in adrenocortical carcinomas

Oliveira, Rui Caetano de; Martins, Maria João; Moreno, Carolina; Almeida, Rui; Carvalho, João; Teixeira, Paulo; Teixeira, Miguel; Silva, Edgar Tavares

Adrenocortical carcinomas (ACC) are aggressive tumors with a poor prognosis. Histological scores are advised for the diagnosis, however, there are borderline cases that may be misjudged as adrenocortical adenomas (ACA). The three main scores used are: Weiss Modified System (WMS), Reticulin Algorithm (RA), and Helsinki Score (HS). We intend to compare the accuracy of the three scores in ACC diagnosis and to iden...


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