28 documents found, page 1 of 3
A new effective heuristic for the Prisoner Transportation Problem
Ferreira, Luciano; Maciel, Marcos Vinicius Milan; Valério de Carvalho, José Manuel; Silva, Elsa; Alvelos, Filipe Pereira eThe Prisoner Transportation Problem is an NP-hard combinatorial problem and a complex variant of the Dial-aRide Problem. Given a set of requests for pick-up and delivery and a homogeneous fleet, it consists of assigning requests to vehicles to serve all requests, respecting the problem constraints such as route duration, capacity, ride time, time windows, multi-compartment assignment of conflicting prisoners an...
MicroRNA-mediated control of mesenchymal stem/stromal cell senescence: A compar...
Giestinhas, Andrea; Moura, Sara Reis; Silva, Elsa; Nascimento, Diana; Almeida, Maria InêsOsteoarthritis is a growing health problem, aggravated by aging. Mesenchymal stem/stromal cells (MSCs) emerged as a promising cell-based therapy for this disease. However, in vitro expansion of MSCs can result in cell senescence. MicroRNAs (miRNAs) are key regulators of senescence pathways, making them attractive targets to decrease senescence. This work aims to identify senescence-related miRNAs, with the long...
A GRASP-based multi-objective approach for the tuna purse seine fishing fleet r...
Granado, Igor; Silva, Elsa; Carravilla, Maria Antónia; Oliveira, José Fernando; Hernando, Leticia; Fernandes-Salvador, Jose A.Nowadays, the world’s fishing fleet uses 20% more fuel to catch the same amount of fish compared to 30 years ago. Addressing this negative environmental and economic performance is crucial due to stricter emission regulations, rising fuel costs, and predicted declines in fish biomass and body sizes due to climate change. Investment in more efficient engines, larger ships and better fuel has been the main respon...
Special issue on “Cutting and Packing”
Moura, Ana; Ramos, António Galrão; Silva, Elsa; Oliveira, José Fernando[Excerpt] This special issue, “Cutting and Packing”, of International Transactions in Operational Research (ITOR), focuses on recent advances in Cutting and Packing (C&P) problems and their applications. Continuing a long tradition of special issues on this topic in OR journals that started in 1990 and builds upon ITOR's successful previous editions in 2009 and 2013, this special issue aims to capture the lates...
Validation of ELPO-PT: a risk assessment scale for surgical positioning injurie...
Salvini, Andreia; Silva, Elsa; Passos, Carmen; Manuel, Tânia; Moraes, Camila; Sousa, Clementina; Alves, PauloBackground/Objectives: Surgical procedures carry inherent risks, including injuries from surgical positioning, which impact patient safety and healthcare quality. An instrument to assess and prevent these injuries is essential. This study aimed to validate and culturally adapt the ELPO-PT for the Portuguese population to ensure its applicability and effectiveness in assessing the risk of injury from surgical po...
Edição especial problemas de corte e empacotamento
Silva, Elsa; Poldi, Kelly[Excerto] Os Problemas de Corte e Empacotamento (PCE) são problemas de otimização combinatória de resolução particularmente difícil, sendo a maioria classificados como NP-hard. Esses problemas surgem em diversas aplicações do mundo real, tanto na indústria quanto nos serviços, sempre que é necessário dividir objetos ou espaços maiores em itens menores, com o objetivo de minimizar o desperdício. Exemplos prático...
Pallets delivery: two matheuristics for combined loading and routing
Silva, Elsa; Ramos, António G.; Moura, AnaThe implementation of novel regulatory and technical requirements for the distribution of vehicle axle weights in road freight transport introduces a new set of constraints on vehicle routing. Until now, axle weight distribution in determining the load plan for freight transport units has been overlooked in the vehicle routing process. Compliance with these axle weight constraints has become paramount for road ...
Impact of minimum distance constraints on sheet metal waste for plasma cutting
Francescatto, Matheus; Júnior, Alvaro Luiz Neuenfeldt; Silva, Elsa; Furtado, João Carlos; Bromberger, DaniWe approached the two-dimensional rectangular strip packing problem (2D-SPP), where the main goal is to pack a given number of rectangles without any overlap to minimize the height of the strip. Real-life constraints must be considered when developing 2D-SPP algorithms to deliver solutions that will improve the cutting processes. In the 2D-SPP literature, a gap related to studies approaching constraints in real...
Cutting and packing problems under uncertainty: literature review and classific...
Hadj Salem, Khadija; Silva, Elsa; Oliveira, José FernandoCutting and packing problems are hard combinatorial optimization problems that arise in several manufacturing and process industries or in their supply chains. The solution of these problems is not only a scientific challenge but also has a large economic impact, as it contributes to the reduction of one of the major cost factors for many production sectors, namely raw materials, together with a positive enviro...
Transporte do recém-nascido de risco: perspetiva dos cuidados de proteção do ne...
Silva, Elsa; Silva, Pedro; Santos, Vera; Boteta, TâniaO recém-nascido (RN) doente e/ou prematuro é único na sua vulnerabilidade. Para além da instabilidade fisiológica pela doença, da imaturidade e da necessidade de cuidados intensivos diferenciados, o seu cérebro está em rápido crescimento e diferenciação e é extremamente permeável a insultos sensoriais e ao stress. Estes fatores têm assim potencial de influenciar de forma deletéria o seu neurodesenvolvimento. Qu...