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Controlled release of Nor-β-lapachone by PLGA microparticles : a strategy for i...

Costa, Marcilia P.; Feitosa, Anderson C. S.; Oliveira, Fátima C. E.; Cavalcanti, Bruno C.; Silva, Eufrânio N. da; Dias, Gleiston G.

Prostate cancer is one of the most common malignant tumors in males and it has become a major worldwide public health problem. This study characterizes the encapsulation of Nor-β-lapachone (NβL) in poly(d,l-lactide-co-glycolide) (PLGA) microcapsules and evaluates the cytotoxicity of the resulting drug-loaded system against metastatic prostate cancer cells. The microcapsules presented appropriate morphological f...

Date: 2016   |   Origin: Oasisbr

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