16 documents found, page 1 of 2
Barriers to hand hygiene in na emergency service according to health professionals
Silva, Filomena; Costa, Pedro; Braga, Fátima; Martins, SilvanaBackground: hand hygiene is considered the simplest and most effective measure to reduce healthcare-associated infections. Objectives: analyze the perception of health professionals in an emergency service about barriers to good hand hygiene practices. Methodology: quantitative, descriptive, correlational and cross-sectional study, developed in a medical-surgical emergency service in Portugal. Data collection u...
Autofluorescência do fundo ocular: dos princípios básicos às aplicações clínicas
Roque, Joana; Almeida, Júlio; Basto, Rita; Henriques, Susana; Pires, Graça; Silva, Filomena; Prieto, IsabelA autofluorescência do fundo ocular (FAF) é um exame de imagem valioso em várias doenças da retina, que poderá ser subutilizado na prática clínica diária. O objectivo deste artigo é rever os princípios básicos da autofluorescência azul e realçar sua utilidade clínica. A FAF é um exame de imagem não invasivo e rápido do fundo ocular. As imagens de FAF reflectem a distribuição da lipofuscina no epitélio pigmentar...
Guidelines das oclusões venosas da retina
Beltrán, Belmira; Silva, Filomena; Roque, José; Flores, Rita; Silva, Rufino MartinsGuidelines
Berberine-induced cardioprotection and Sirt3 modulation in doxorubicin-treated ...
Coelho, Ana R.; Martins, Tatiana R.; Couto, Renata; Deus, Cláudia; Pereira, Cláudia V.; Simões, Rui F.; Rizvanov, Albert A.; Silva, FilomenaDoxorubicin (DOX) is one of the most widely used anti-neoplastic agents. However, treatment with DOX is associated with cumulative cardiotoxicity inducing progressive cardiomyocyte death. Sirtuin 3 (Sirt3), a mitochondrial deacetylase, regulates the activity of proteins involved in apoptosis, autophagy and metabolism. Our hypothesis is that pharmacological modulation by berberine (BER) pre-conditioning of Sirt3...
Amaurose Súbita e Doença Falciforme: A Propósito de um Caso
F. Oliveira, Joana; Nunes, Pedro; Ferreira, Teresa; Correia, Paula; Dias, Alexandra; Teixeira, Susana; Silva, Filomena; Bernardo, ManuelaOs autores apresentam o caso clínico de uma criança com doença falciforme, internada por choque séptico com meningite e pneumonia a Streptococcus pneumoniae. No decurso do internamento surgiu amaurose súbita à esquerda e herpes mucocutâneo labial. O exame oftalmológico foi sugestivo de oclusão arterial no olho esquerdo e de necrose retiniana viral à direita, pelo que foi instituída terapêutica antiviral e antic...
Resveratrol inclusion complexes: Antibacterial and anti-biofilm activity agains...
Duarte, Andreia; Alves, Ana C.; Ferreira, Susana; Silva, Filomena; Domingues, F.C.Worldwide, the consumption or handling of contaminated food has been described as one of the major causes of foodborne illness with campylobacteriosis being the most commonly reported zoonosis. Campylobacter jejuni and Campylobacter coli are considered the major cause of bacterial gastroenteritis, while Arcobacter spp. are also known to be human and animal pathogens. Furthermore, these bacteria are able to form...
Resveratrol production in bioreactor: Assessment of cell physiological states a...
Afonso, Margarida S.; Ferreira, Susana; Domingues, F.C.; Silva, FilomenaResveratrol is a plant secondary metabolite commonly found in peanuts and grapevines with significant health benefits. Recombinant organisms can produce large amounts of resveratrol and, in this work, Escherichia coli BW27784 was used to produce resveratrol in bioreactors while monitoring cell physiology and plasmid stability through flow cytometry and real-time qPCR, respectively. Initially, the influence of c...
Strategies to improve the solubility and stability of stilbene antioxidants: a ...
Silva, Filomena; Figueiras, Ana; Gallardo, Eugenia; Nerín, Cristina; Domingues, Fernanda C.Aiming at the development of an active food packaging, the goal of this study was to increase stilbenes (resveratrol (RV), pterostilbene (PT) and pinosylvin (PS)) aqueous solubility and stability using hydropropyl-cyclodextrins (HP-CDs) and bile salts. To evaluate stilbene concentration, an HPLC-DAD method was validated. Stilbene solubility was improved by the formation of inclusion complexes and micellar syste...
Resveratrol against Arcobacter butzleri and Arcobacter cryaerophilus: Activity ...
Ferreira, Susana; Silva, Filomena; Queiroz, João; Oleastro, Mónica; Domingues, F.C.The frequent isolation of Arcobacter butzleri and Arcobacter cryaerophilus from food samples makes it imperative to search for potential compounds able to inhibit the development of these bacteria. Taking this into consideration, this study focuses on the antimicrobial activity of resveratrol and its mechanism of action against A. butzleri and A. cryaerophilus. The activity of resveratrol was assessed by a micr...
Biofunctionalization of cellulosic fibres with l-cysteine: Assessment of antiba...
Caldeira, Estela; Piskin, Erhan; Granadeiro, Luiza Breitenfeld; Silva, Filomena; Gouveia, Isabel C.The main purpose of this work is to obtain a cotton-based textile material functionalized with l-cysteine (l-cys) to achieve an antimicrobial effect with potential application in biomedical, geriatric or pediatric textiles. The binding capacity of l-cys to cotton fibres was assessed through different functionalization strategies—surface activation and exhaustion processes. A subsequent analysis of the possible ...