20 documents found, page 1 of 2

Development of biomimetic human nails using electrospun keratin nanofibers and ...

Introduction: Nail infections, particularly onychomycosis, affect approximately 5.5% of the global population, significantly impacting quality of life. Beyond aesthetic concerns, these conditions cause discomfort, functional impairment, and psychological distress. A major challenge in treatment is the low transungual permeability of the nail plate, restricting drug penetration and reducing therapeutic efficacy....

The Impact of Sleep on Haematological Parameters in Firefighters

Sleep is a vital process that impacts biological functions such as cell renewal, bone regeneration, and immune system support. Disrupted sleep can interrupt erythropoiesis, leading to fewer red blood cells, reduced haemoglobin concentration, and decreased haematocrit levels, potentially contributing to haematological disorders. This is particularly concerning for shift workers for example firefighters. While pr...

TrkC Intracellular Signalling in the Brain Fear Network During the Formation of...

Learned fear is orchestrated by a brain fear network that comprises the amygdala, hippocampus and the medial prefrontal cortex. Synaptic plasticity within this network is critical for the formation of proper fear memories. Known for their role in the promotion of synaptic plasticity, neurotrophins position as obvious candidates in the regulation of fear processes. Indeed, recent evidence from our laboratory and...

Firefighters' sleep quality: results of a study in The Northeast of Portugal

The aim of this study was to evaluate and describe the overall sleep quality of firefighters. Application of the Portuguese version of the Pittsburgh Sleep Quality Index (PSQI) to firefighters, from the Northeast of Portugal, who accepted to participate in the study. Data collected between June 2021 and July 2022. The PSQI global score classified participants as 36,9% of participants as poor sleepers, although ...

On the Topic of Impossibility: a question-sensitive impossible worlds approach ...

Desde que Hintikka (1962) propôs uma lógica epistémica modal com base na semântica de mundos possíveis que rapidamente se colocou o problema da omnisciência lógica, isto é, de que a lógica em questão implica que os agentes sabem tudo o que se segue logicamente do que sabem. O próprio Hintikka (1975) tentou resolver o problema introduzindo “mundos possíveis impossíveis”. Desde então, os mundos impossíveis têm si...

Salmonella peritonitis in an automated peritoneal dialysis patient- Case report

Peritonitis remains one of the main complications of peritoneal dialysis (PD) and one of the main reasons for abandoning this treatment and switching to hemodialysis. It also accounts for considerable mortality and hospitalization among PD patients. Most cases of peritonitis related to PD result from the contamination caused by the poor management of the Tenckhoff catheter by the patient or care-provider. The m...

Criatividade no turismo e envolvimento do visitante: o estudo de caso de Loulé ...

A criatividade aponta à experiência do consumidor pós-moderno a uma maior evidência do patrimônio local, tornando-se num recurso alternativo para o desenvolvimento turístico. O principal objetivo do presente estudo consiste em discutir o papel e influência da imagem no comportamento de compra do consumidor, em contextos específicos de turismo (isto é turismo criativo). Pretende-se compreender de que forma turis...

IgA dominant glomerulonephritis associated to staphylococcus infection: a pecul...

IgA dominant glomerulonephritis associated to Staphylococcus infection is a rare clinical entity that has been described mainly in case reports. Biopsy features can resemble other disease entities mainly IgA nephropathy and Henoch‑Schönlein purpura nephritis. Treatment of IgA dominant glomerulonephritis associated to staphylococcal infection is based on antibiotics for the underlying infection, controlling hype...

Impact of industry's 4.0 technologies in the portuguese footwear industry

Supported Ionic liquids as alternative adsorbents for the removal of cytostatic...