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Prediction of Hepatocellular Carcinoma in a Portuguese Population after Hepatit...

Mascarenhas, André; Serrazina, Juliana; Bronze, Sérgio; Cortez-Pinto, Helena; Presa, José; Barreira, Ana; Carrola, Paulo; Vara-Luiz, Francisco

Introduction: Chronic infection with hepatitis C virus (HCV) causes 25% of hepatocellular carcinoma (HCC) cases worldwide, a major cause of morbimortality even after sustained virologic response (SVR). Universal screening to all patients with advanced liver fibrosis is currently recommended. A risk-based strategy could improve the detection rate of early HCC and diminish the surveillance burden. Although severa...


Technological Innovations in Hepatitis C Screening and Diagnosis: Focused Liter...

Botto, Inês; Rodrigues, Inês; Bronze, Sérgio; Medina, Diogo; Freire, Rita; Serejo, Fátima

Introduction: Current Portuguese hepatitis C virus (HCV)screening guidance (2017) limits confirmation of antibody--positive test results to hospital specialist visits, using nucleic acid amplification tests (NAAT). No other professionals, healthcare settings, or testing technologies are included, despite innovations toward more patient-centric care. Methods: We performed a focused review of literaturepublished ...


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