4 documents found, page 1 of 1
Chitosan membrane modified with a new Zinc(ii)-vanillin complex improves skin w...
Tavares, Emanuella de Aragão; Medeiros, Wendy Marina Toscano Queiroz de; Pontes, Talita Pereira de Assis; Barbosa, Maisie Mitchele BarbosaThe treatment of chronic wounds is considered a public health problem. When the condition affects at-risk groups such as those with diabetics, it becomes a great clinical challenge. In this work, we evaluated the healing effects of a new zinc complex, [Zn(phen)(van)2], identified as ZPV, which was synthesized, characterized and associated with chitosan (CS) membranes and tested on cutaneous wounds of diabetic r...
Preconditioning with a novel metallopharmaceutical NO donor in anesthetized rat...
Oriá, Reinaldo Barreto; Lopes, Luiz Gonzaga de França; Brito, Gerly Anne de Castro; Santos, Armenio Aguiar dos; Vasconcelos, Raquel Cavalcante deRut-bpy is a novel nitrosyl–ruthenium complex releasing NO into the vascular system. We evaluated the effect of Rut-bpy (100 mg/kg) on a rat model of brain stroke. Forty rats were assigned to four groups (Saline solution [SS], Rut-bpy, SS?ischemia–reperfusion [SS?I/ R] and Rut-bpy?ischemia–reperfusion [Rut-bpy?I/R]) with their mean arterial pressure (MAP) continuously monitored. The groups were submitted (SS?I/...
Síntese, caracterização e reatividade de novos nitrosilo complexos de rutênio, ...
Silva, Francisco Ordelei Nascimento daIn this work were carried out the synthesis, characterization and the reactivity study of the cis-[Ru(bipy)2LNO](PF6)n (L = imidazole, isonicotinamide and sulphite) and trans-[Ru(bipy)2SO3NO](PF6) complexes, aiming the modulation of the nitrosyl complexes that can act as NO donors in biological systems. The infrared spectra of the cis-[Ru(bipy)2LNO](PF6)n and trans-[Ru(bipy)2SO3NO](PF6) complexes presented ν(NO...
Estudo cinético da reação dos complexos cis-[Ru(bpy)2ImN(NO)](PF6)3 e cis-[Ru(b...
Silva, Francisco Ordelei Nascimento daThe oxide nitric (NO) is a responsible endogenous species by dilation of the blood vessels, being also active in the brain and in other physiologic processes. Donors of NO are pathophysiologically active healthy substances that liberate spontaneously or they are metabolized. Sodium nitroprusside, Na2[Fe(CN)5NO].2H2O, is part of a class of compounds that liberate NO spontaneously and it is the only metallic comp...