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Atrial fibrillation ablation : the added value of adenosine test in confirming ...

Nunes-Ferreira, Afonso; R. Agostinho, João; Cortez-Dias, Nuno; Silva, G. Lima da; Francisco, Ana Rita; Guimarães, T.; Gonçalves, I. Santos

Introduction: Adenosine test has been increasingly used to confirm pulmonary vein isolation (PVI) in patients undergoing ablation of atrial fibrillation (AF). However, its impact on the success of ablation remains unknown. Purposes: To evaluate the results of the adenosine triphosphate (ATP) test in patients undergoing PVI and assess the success of ablation related to the use of this test (adenosine-guided PVI ...


Cardiotoxicity in haematological diseases : are the tyrosine kinase inhibitors ...

Francisco, A. R. Gaspar Lopes; Alves, D.; Gonçalves, I. S.; Menezes, M. N.; Silva, G. Lima da; Guimarães, T.; David, C.; Braga, J.; Guerra, L.

Introduction: Chemotherapy-induced cardiotoxicity is a growing concern. The true cardiotoxic impact of new drugs such as tyrosine kinase inhibitors is unknown, especially the ones used for chronic myeloid leukaemia. We aim to evaluate nilotinib and imatinib induced cardiotoxicity. Methods: Single-center prospective study of consecutive patients with chronic myeloid leukaemia treated with tyrosine kinase inhibit...


Difference of late potentials detected by signal-averaged ECG in patients with ...

Agostinho, J. A. Ribeiro; António, P.; Dias, N. Cortez; Silva, G. Lima da; Guimarães, T.; Francisco, A. R.; Gonçalves, I.; Paixão, A.; Paiva, S.

Introduction: Brugada syndrome (BrS) patients (pts) with spontaneous type 1 electrocardiographic (ECG) pattern (sT1ECGp) have a greater arrhythmic risk compared to those with fleicainide-induced type 1 ECG pattern (iT1ECGp). However, when the analysis is restricted to asymptomatic pts, the type 1 spontaneous pattern loses its independent prognostic value. Late potentials (LP) obtained by signal-averaged ECG (SA...


Prognostic impact of invasive hemodynamic evaluation in patients with pulmonary...

Ricardo, I. Aguiar; Plácido, R.; Gonçalves, I.; Agostinho, J.; Silva, G. Lima da; Menezes, M. Nobre; Francisco, A. R.; Santos, R.; Ferreira, A.

Introduction: Invasive hemodynamic evaluation is a fundamental diagnostic method in patients with pulmonary hypertension (PH). However, its prognostic value in this group of patients is not fully established. Purpose: To assess the prognostic impact of hemodynamic parameters of right catheterization in patients with PH. Methods: Prospective observational study of patients with PH undergoing right and left cathe...


Implantation of ICD and CRT-D in the elderly population : will it be a limiting...

Ricardo, I. Aguiar; Dias, Nuno Cortez; Marques, P.; Magalhães, A.; Gonçalves, I.; Agostinho, J.; Silva, G. Lima da; Guimarães, T.; Santos, I.

Introduction: Implantable cardioverter defibrillator (ICD) and cardiac resynchronization (CRT-D) implantation in elderly patients is effective in preventing sudden death, although limited by the natural shorter life expectancy. The different device brands present very variable survival estimates and it has been discussed the availability of less expensive, less longevity generators for the elderly population. P...


Prognostic significance of disrhythmias in patients with familiar amyloid polyn...

Francisco, A.R. Gaspar Lopes; Dias, N. Cortez; Menezes, M. N.; Guimarães, T.; Silva, G. Lima da; Plácido, R.; Magalhães, A.; Inácio, C.

Background: Rhythm disturbances and conduction defects are common consequences of cardiac amyloid infiltration in familial amyloid polyneuropathy (FAP) V30M-TTR. The occurrence of dysrhythmias appears to increase with the severity of the disease but its prognostic value is still unknown. Purpose: To evaluate the occurrence of arrhythmias according to the patient's age and the duration of symptoms and to analyze...


Leukaemic myocardial infiltration presenting as acute heart failure

Silva, G. Lima da; Valle, S.; Pinto, Fausto J.; Almeida, Ana G.


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