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Toll-like receptor-1 single-nucleotide polymorphism 1805T/G is associated with ...

Barletta-Naveca, Raphaela Honorato; Naveca, Felipe Gomes; Almeida, Vanessa Alves de; Porto, Jorge Ivan Rebelo; Silva, George Allan Villarouco da

Tuberculosis (TB), caused by mycobacterial species of the Mycobacterium tuberculosis complex, is a serious global health issue. Brazil is among the 22 countries with the highest number of TB cases, and the state of Amazonas has the highest incidence of TB cases in the country. Toll-like receptors (TLRs) are important pattern recognition receptors of the innate immunity and play a key role in orchestrating an ef...

Date: 2020   |   Origin: Oasisbr

Identification of primary drug resistance to rifampin in mycobacterium leprae s...

Mejía, Matilde Del Carmen Contreras; dos Santos, Maísa Porto; Silva, George Allan Villarouco da; Motta-Passos, Isabella da; Naveca, Felipe Gomes

The aim of this study was to identify polymorphisms in the folp1, gyrA, and rpoB genes in leprosy patients treated in Amazonas State, Brazil. Among 197 slit-skin smear samples from untreated or relapsed patients, we found three cases of primary resistance to rifampin and one confirmed case of multidrug resistance. Copyright © 2014, American Society for Microbiology. All Rights Reserved.

Date: 2020   |   Origin: Oasisbr

Analysis of the immunological biomarker profile during acute zika virus infecti...

Naveca, Felipe Gomes; Pontes, Gemilson Soares; Chang, Aileen Yu Hen; Silva, George Allan Villarouco da; Nascimento, Valdinete Alves do

BACKGROUND Infection with Zika virus (ZIKV) manifests in a broad spectrum of disease ranging from mild illness to severe neurological complications and little is known about Zika immunopathogenesis. OBJECTIVES To define the immunologic biomarkers that correlate with acute ZIKV infection. METHODS We characterized the levels of circulating cytokines, chemokines, and growth factors in 54 infected patients of both ...

Date: 2020   |   Origin: Oasisbr

Associa????o de polimorfismos dos genes IL1B, IFNG e n??veis de citocinas com a...

Silva, George Allan Villarouco da

Submitted by George Silva (georgevillarouco@hotmail.com) on 2019-10-15T03:32:26Z No. of bitstreams: 4 Tese Final _ George 2019_vers??o_corrigida_p??s_defesa.pdf: 913705 bytes, checksum: bc43266c705d448235dbe7829843b617 (MD5) Carta_encaminhamento_autodeposito.pdf: 1705060 bytes, checksum: 361f95865bdb43b1d22362b2c53c471a (MD5) Ata_Defesa_Doutorado_George.pdf: 307778 bytes, checksum: aaa77d51de41fd99c547ec6581927...

Date: 2019   |   Origin: Oasisbr

Avalia????o de polimorfismos gen??ticos de L12RB2 e IFN-y em pacientes portador...

Silva, George Allan Villarouco da

Submitted by Divis??o de Documenta????o/BC Biblioteca Central (ddbc@ufam.edu.br) on 2016-02-01T14:39:07Z No. of bitstreams: 1 Reprodu????o N??o Autorizada.pdf: 47716 bytes, checksum: 0353d988c60b584cfc9978721c498a11 (MD5); Approved for entry into archive by Divis??o de Documenta????o/BC Biblioteca Central (ddbc@ufam.edu.br) on 2016-02-01T14:39:34Z (GMT) No. of bitstreams: 1 Reprodu????o N??o Autorizada.pdf: 477...

Date: 2016   |   Origin: Oasisbr

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