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Apoptosis in human liver carcinoma caused by gold nanoparticles in combination ...

Araújo Júnior, Raimundo Fernandes de; Pessoa, Jonas B.; Cruz, Luis J.; Chan, Alan B.; Miguel, Emilio de Castro; Cavalcante, Rômulo S.

In cancers, apoptosis signaling pathways and cell survival and growth pathways responsible for resistance to conventional treatments, such as Pi3K/Akt/mTOR and mitogen-activated protein kinase (MAPK) become dysregulated. Recently, alternative treatments to promote tumor cell death have become important. The present study reports on the antitumor and cytoprotective action of gold nanoparticles (GNPs) and carvedi...

Date: 2022   |   Origin: Oasisbr

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