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Effects of ketamine administration on mTOR and reticulum stress signaling pathw...
Abelaira, Helena M.; Réus, Gislaine Z.; Ignácio, Zuleide M.; Santos, Maria Augusta B. dos; Moura, Airam B. de; Matos, Danyela; Demo, Júlia P.Recent studies show that activation of the mTOR signaling pathway is required for the rapid antide- pressant actions of glutamate N-methyl-D-aspartate (NMDA) receptor antagonists. A relationship be- tween mTOR kinase and the endoplasmic reticulum (ER) stress pathway, also known as the unfolded protein response (UPR) has been shown. We evaluate the effects of ketamine administration on the mTOR signaling pathway...
Data: 2017
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Origem: Oasisbr