5 documents found, page 1 of 1
Portuguese Recommendations for the Use of Biological and Targeted Synthetic Dis...
Fernandes, BM; Guimarães, F; Almeida, DE; Neto, A; Tavares-Costa, J; Roxo Ribeiro, A; Quintal, A; Pereira, JP; Silva, L; Nóvoa, TS; Faustino, A; Vaz, CObjective: To update the recommendations for the treatment of rheumatoid arthritis (RA) with biological and targeted synthetic disease-modifying antirheumatic drugs (bDMARDs and tsDMARDs), endorsed by the Portuguese Society of Rheumatology (SPR). Methods: These treatment recommendations were formulated by Portuguese rheumatologists taking into account previous recommendations, new literature evidence and consen...
Portuguese recommendations for the use of biological and targeted synthetic dis...
Fernandes, Bruno Miguel; Guimarães, F; Almeida, DE; Neto, A; Tavares-Costa, J; Ribeiro, AR; Quintal, Alberto; Pereira, JP; Silva, L; Nóvoa, TSObjective: To update the recommendations for the treatment of rheumatoid arthritis (RA) with biological and targeted synthetic disease-modifying antirheumatic drugs (bDMARDs and tsDMARDs), endorsed by the Portuguese Society of Rheumatology (SPR). Methods: These treatment recommendations were formulated by Portuguese rheumatologists taking into account previous recommendations, new literature evidence and consen...
Mutational Analysis of Portuguese Families with Multiple Endocrine Neoplasia Ty...
Cavaco, B; Domingues, R; Bacelar, MC; Cardoso, H; Barros, L; Gomes, L; Ruas, MMA; Agapito, A; Garrão, A; Pannett, A; Silva, JL; Sobrinho, LGOBJECTIVE: To determine the spectrum of MEN1 mutations in Portuguese kindreds, and identify mutation-carriers. PATIENTS, DESIGN AND RESULTS: Six unrelated MEN1 families were studied for MEN1 gene mutations by single-strand conformational polymorphism (SSCP) and DNA sequence analysis of the coding region and exon-intron boundaries of the MEN1 gene. These methods identified 4 different heterozygous mutations in f...
Mumps epidemic in Portugal despite high vaccine coverage : preliminary report
Dias, JA; Cordeiro, M; Afzal, MA; Freitas, Maria Graça; Morgado, MR; Silva, JL; Nunes, LM; Lima, MG; Avilez, FA measles, mumps, and rubella (MMR) trivalent vaccine was added to Portugal’s National Immunisation Programme (NIP) in 1987. All vaccines are given at health centres, free of charge, but an epidemic of mumps began in 1995, firstly in northern Portugal and has now spread to other areas. Initially, only one dose of MMR vaccine at the age of 15 months was recommended. In 1990 a second dose at the age of 11 to 13 y...
Neurofibromatose de Von Recklinghausen e Feocromocitoma Maligno: Apresentação d...
Ventura, A; Ribeiro, J; Murinello, A; Amado, L; Morgado, A; Guerra, C; Murinello, F; Silva, JL; Mota, JAA neurofibromatose é uma doença que pode afectar todos os órgãos. As suas manifestações clínicas podem ser muito variáveis e associam-se-lhe, frequentemente, neoplasias. é o caso do feocromositoma, que na sua forma benigna, coexiste em 10 % dos casos; contudo, a descrição da associação com a forma maligna é uma raridade, o que justifica o interesse da divulgação da nossa experiência. Salientamos, no entanto, qu...