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Gingerol fraction from zingiber officinale nephrotoxicity protects against gent...
Rodrigues, Francisco A. P.; Prata, Mara M. G.; Oliveira, Iris Cristina Maia; Alves, Natacha Teresa Queiroz; Freitas, Rosa E. M.; Monteiro, Helena S. A.Nephrotoxicity is the main complication of gentamicin (GM) treatment. GM induces renal damage by overproduction of reactive oxygen species and inflammation in proximal tubular cells. Phenolic compounds from ginger, called gingerols, have been demonstrated to have antioxidant and anti-inflammatory effects. We investigated if oral treatment with an enriched solution of gingerols (GF) would promote a nephroprotect...
Date: 2014
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Origin: Oasisbr