Acute kidney injury (AKI) and metabolic dysfunction are critical complications in sepsis syndrome; however, their pathophysiological mechanisms remain poorly understood. Therefore, we evaluated whether the pharmacological properties of 6-gingerol (6G) and 10-gingerol (10G) could modulate AKI and metabolic disruption in a rat model of sepsis (faecal peritonitis). Animals from the sham and AKI groups were intrape...
CANDIDO, Pedro Mateus Sales de Oliveira;RODRIGUES, Francisco Adelvane de Paulo;SILVA, James Almada da; RODRIGUES, Tamara Silva;BINDA, Alexandre Havt. [6] - Gingerol isolado do gengibre (zingiber officinale roscoe) modula as alterações renais causadas pela septicemia induzida em modelo animal. Revista Encontros Universitários da UFC, Fortaleza, v. 1, n. 1, 2016. (Encontro de Iniciação Científica, 35); O presente...
Financiadora de Estudos e Projetos; Ten herbs used in traditional medicine supported by literature for its effectiveness to osteoarticular diseases were selected to conduct a screening of inhibition activity against the cathepsin K, an important enzyme responsible for cleavage of collagen, the main constituent of extracellular matrix of cartilage and bone. Out of the ten herbs selected (ginger, saffron, camelli...