12 documents found, page 1 of 2
Food addiction: prevalence, psychopathological correlates and associations with...
Nunes-Neto, Paulo R.; Köhler, Cristiano A.; Schuch, Felipe B.; Solmi, Marco; Quevedo, João; Maes, Michael; Murru, Andrea; Vieta, EduardObjective: To determine the prevalence of food addiction in a large Brazilian non-clinical sample. Sociodemographic and psychopathological correlates of food addiction as well as associations with quality (QoL) domains were also investigated. Methods: This cross-sectional study obtained data from a Brazilian anonymous web-based research platform (N = 7639; 71.3% females). Participants provided sociodemographic ...
The putative role of oxidative stress and inflammation in the pathophysiology o...
Morris, Gerwyn; Stubbs, Brendon; Köhler, Cristiano A.; Walder, Ken; Slyepchenko, Anastasiya; Berk, Michael; Carvalho, André F.Sleep and circadian abnormalities are prevalent and burdensome manifestations of diverse neuro-immune diseases, and may aggravate the course of several neuropsychiatric disorders. The underlying pathophysiology of sleep abnormalities across neuropsychiatric disorders remains unclear, and may involve the inter-play of several clinical variables and mechanistic pathways. In this review, we propose a heuristic fra...
Imaging genetics paradigms in depression research: systematic review and meta-a...
Pereira, Lícia P.; Köhler, Cristiano A.; Stubbs, Brendon; Miskowiak, Kamilla W.; Morris, Gerwyn; Freitas, Bárbara P. de Freitas; Thompson, TrevorImaging genetics studies involving participants with major depressive disorder (MDD) have expanded. Nevertheless, findings have been inconsistent. Thus, we conducted a systematic review and meta-analysis of imaging genetics studies that enrolled MDD participants across major databases through June 30th, 2017. Sixtyfive studies met eligibility criteria (N=4034 MDD participants and 3293 controls), and there was s...
Gut microbiota, bacterial translocation, and interactions with diet : pathophys...
Slyepchenko, Anastasiya; Maes, Michael; Jacka, Felice N.; Köhler, Cristiano A.; Barichello, Tatiana; McIntyre, Roger S.; Berk, Michael; Grande, IriaBackground: Persistent low-grade immune-inflammatory processes, oxidative and nitrosative stress (O&NS), and hy- pothalamic-pituitary-adrenal axis activation are integral to the pathophysiology of major depressive disorder (MDD). The microbiome, intestinal compositional changes, and re-sultant bacterial translocation add a new element to the bi- directional interactions of the gut-brain axis; new evidence impli...
Depression in cancer : the many biobehavioral pathways driving tumor progression
Bortolato, Beatrice; Hyphantis, Thomas N.; Valpione, Sara; Perini, Giulia; Maes, Michael; Morris, Gerwyn; Kubera, Marta Kubera; Köhler, Cristiano A.Major Depressive Disorder (MDD) is common among cancer patients, with prevalence rates up to four- times higher than the general population. Depression confers worse outcomes, including non- adherence to treatment and increased mortality in the oncology setting. Advances in the understanding of neurobiological underpinnings of depression have revealed shared biobehavioral mechanisms may contribute to cancer pro...
The search for neuroimaging and cognitive endophenotypes: A critical systematic...
Miskowiak, Kamilla W.; Kjærstad, Hanne L.; Meluken, Iselin; Petersen, Jeff Zarp; Maciel, Beatriz R.; Köhler, Cristiano A.; Vinberg, MajThe phenomenology and underlying pathophysiology of bipolar disorder (BD) are heterogeneous. The identification of putative endophenotypes for BD can aid in the investigation of unique patho-etiological pathways, which may lead to the development of personalised preventative and therapeutic approaches for this multi-faceted disorder. We included original studies involving unaffected first-degree relatives of BD...
An exploratory study of the heterogeneity of the jealousy phenomenon and its as...
Lima, Amanda B.; Köhler, Cristiano A.; Stubbs, Brendon; Quevedo, João; Hyphantis, Thomas N.; Koyanagi, Ai; Marazziti, Donatella; Soares, Jair C.Background: Jealousy is a heterogenous emotion on a spectrum from normality to psychopathology. The relation- ship between di ff erent jealousy subtypes/dimensions and a ff ective temperaments remain unknown. In addition, few large surveys have investigated the associations between jealousy subtypes and psychopathological dimensions. Methods: A Brazilian Portuguese version of the “ Questionario della Gelosia ” ...
Measuring affective temperaments: a systematic review of validation studies of ...
Elias, Liana Rosa; Köhler, Cristiano A.; Stubbs, Brendon; Maciel, Beatriz R.; Cavalcante, Lígia M.; Vale, Antonio M. O.; Gonda, Xénia; Quevedo, JoãoBackground: The assessment of a ff ective temperaments has provided useful insights for the psychopatholo- gical understanding of a ff ective disorders and for the conceptualization of bipolar spectrum disorders. The Temperament in Memphis Pisa and San Diego (TEMPS) instrument has been widely used in research, yet its psychometric properties and optimal factor structure are unclear. Methods: The PubMed/MEDLINE,...
Systematic assessment of environmental risk factors for bipolar disorder : an u...
Bortolato, Beatrice; Köhler, Cristiano A.; Evangelou, Evangelos; León-Caballero, Jordi; Solmi, Marco; Stubbs, Brendon; Belbasis, LazarosObjectives: The pathophysiology of bipolar disorder is likely to involve both genetic and environmental risk factors. In our study, we aimed to perform a systematic search of environmental risk factors for BD. In addition, we assessed possible hints of bias in this literature, and identified risk factors supported by high epidemiological credibility. Methods: We searched the Pubmed/MEDLINE, EMBASE and PsycInfo ...
The relationship between genetic risk variants with brain structure and functio...
Pereira, Licia P.; Köhler, Cristiano A.; Sousa, Rafael T. de; Solmi, Marco; Freitas, Bárbara P. de; Fornaro, Michele; Machado-Vieira, RodrigoGenetic-neuroimaging paradigms could provide insights regarding the pathophysiology of bipolar disorder (BD). Nevertheless, fi ndings have been inconsistent across studies. A systematic review of gene-imaging studies involving individuals with BD was conducted across electronic major databases from inception until January 9th, 2017. Forty-four studies met eligibility criteria (N = 2122 BD participants). Twenty-...