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Multi-sided platforms as catalysts for responsible innovation in healthcare

Tria, Gemma; Jacinto, Maria João; Oliveira, Margarida; Canhão, Helena; Oliveira, Pedro

Healthcare systems face increasing pressure from aging populations, chronic diseases, and the demand for accessible, high-quality care. Yet many innovations fail to address the needs of vulnerable groups. This study examines Responsible Innovation (RI) in healthcare through the Patient Innovation (PI) multi-sided platform (MSP) case. Using a mixed-methods approach, it explores how patient-driven solutions can b...


Innovations developed by patients and informal caregivers for needs associated ...

Jacinto, Maria João; Oliveira, Pedro; Canhão, Helena

Until recently, innovation in healthcare was mainly achieved through the development of new drugs, therapies, and medical devices by big pharma and medtech companies; however, the innovative potential for this field is much broader. The patients and caregivers' role in healthcare is often associated with disease management, demand for their own illness data, and its exchange with other patients. However, the pa...


Transcriptional profiling in Saccharomyces cerevisiae relevant for predicting a...

Gil, Fátima N.; Gonçalves, Alina C.; Jacinto, Maria João; Becker, Jörg D.; Viegas, Cristina A.

Alachlor has been a commonly applied herbicide and is a substance of ecotoxicological concern. The present study aims to identify molecular biomarkers in the eukaryotic model Saccharomyces cerevisiae that can be used to predict potential cytotoxic effects of alachlor, while providing new mechanistic clues with possible relevance for experimentally less accessible eukaryotes. It focuses on genome-wide expression...


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