1 document found, page 1 of 1
Sort by
Issue Date
Tau protein is essential for stress-induced brain pathology
Lopes, Sofia; Silva, João Vaz; Pinto, Vítor; Dalla, Christina; Kokras, N.; Bedenk, Benedikt; Mack, Natalie; Czisch, Michael; Almeida, Osborne F. X.Exposure to chronic stress is frequently accompanied by cognitive and affective disorders in association with neurostructural adaptations. Chronic stress was previously shown to trigger Alzheimer's-like neuropathology, which is characterized by Tau hyper-phosphorylation and missorting into dendritic spines followed by memory deficits. Here, we demonstrate that stress-driven hippocampal deficits in wild-type mic...
Date: 2016
|
Origin: RepositóriUM - Universidade do Minho