357 documents found, page 1 of 36
Substituição da formalina neutra a 10% por agave na fixação de material biológi...
Almeida, Beatriz; Silva, Joana; Maria, Mariana; Cunha, Gilda; Mendonça, Paula; Ladeira, CarinaA utilização de formaldeído na fixação de amostras biológicas apresenta riscos para a saúde humana e ambiente, devido à sua toxicidade e potencial carcinogénico, realçando a necessidade de encontrar alternativas mais seguras e sustentáveis. O objetivo deste estudo é testar o agave como fixador biológico, comparando os seus resultados com os da formalina neutra tamponada a 10% (FNT a 10%) em termos de preservaçã...
Substituição da formalina neutra a 10% por agave na fixação de material biológi...
Almeida, Beatriz; Silva, Joana; Maria, Mariana; Cunha, Gilda; Mendonça, Paula; Ladeira, CarinaA fixação de tecidos biológicos é essencial para preservar a estrutura celular ao evitar a autólise. O formaldeído, comummente usado sob a forma de formalina (solução aquosa de 37-40% de formaldeído), é o mais usado, por ter baixo custo e grande poder de penetração nos tecidos, com artefactos de retração reduzidos, no entanto apresenta riscos para a saúde humana e ambiente, devido à sua toxicidade e potencial c...
Music as a communication strategy
Silva, JoanaMusic has several powers, among them the best known, its influence on emotions and its association with memories. However, it is also a strategic form of communication and a bridge to manipulate consumer behavior. This article analyses how music constitutes a communication element, taking into account its role in buildinseg brand identity and in remembering advertising messages. The methodology is bad on the re...
Positive emotional memories, stigma, and mental health in sexual and gender min...
Palmeira, Lara; Silva, Joana; Veloso, Bruna; Xavier, AnaLiterature reveals that memories of warmth and safeness, self-compassion, and social support are positively related to mental health. The present study aimed to analyze the impact of early memories of warmth and safeness and internalized homophobic stigma on mental health, through self-compassion and perceived social support, in sexual and gender minority adults. With a cross-sectional design, this study includ...
I Know What I Have to Do, but I Don’t Do It”: The Relationship Between Knowledg...
Silva, Joana; Antunes, Cristina; Batista, Samanta; Braga, José Luís; Gomes, Angélica; Guedes, Rosa; Barbosa, Anabela; Forte, Pedro; Imaginário, CristinaThis study aims to analyze the correlation between healthcare professionals’ knowledge of hand hygiene protocols and their actual adherence to these practices. Specifically, we investigate whether higher knowledge levels correspond to better compliance, and we examine potential influencing factors such as professional role, gender, and prior training in infection control. Methods: A non-probabilistic, convenien...
Mediterranean temporary pond restoration invcreases bat species richness but no...
Silva, Joana; Cruz, Carla; Marques, J. TiagoClimate change scenarios predict a continued decrease in rainfall across the Mediterranean regions in the next years, emphasizing concerns about water scarcity. The ongoing destruction, modification, and drainage of wetland habitats further intensifies this risk to the landscape. Ponds are vulnerable aquatic habitats that supply essential ecosystem services and provide foraging and drinking resources to bats. T...
Synthesis, Characterization, and Biological Effects of Chloro-Cathinones: Toxic...
Gomes, Ana Patrícia; Ferro, Raquel; Pinto, Daniela; Silva, Joana; Alves, Celso; Pacheco, Rita; Gaspar, HelenaCathinones, a class of synthetic new psychoactive substances (NPSs), continue to emerge and pose public threats. Government control efforts often lead to the emergence of new isomers, which have adverse repercussions on NPSs identification and risk prediction. This work reports on the synthesis and structural characterization of twenty chloro-cathinones, including different isomers, to create analytical data to...
Becker Muscular Dystrophy in Pediatric Population: Diagnosis, Genetic Variabili...
Ribeiro, Mário; Silva, Joana; Gonçalves, Ana; Santos, Manuela; Garrido, CristinaIntroduction: Becker muscular dystrophy (BMD) is an X-linked neuromuscular disease caused by variants in the DMD gene that leads to progressive muscle weakness, dilated cardiomyopathy, and neurodevelopmental issues. Objective: To characterize patients with BMD from a pediatric neuromuscular disease center. Methods: Retrospective and descriptive study of BMD patients diagnosed between January 1995 and May 2024. ...
Burden of Disease and Cost of Illness of Triple-Negative Breast Cancer in Portu...
Silva, Joana; Sousa, Gabriela; Costa, Luís; Brito, Margarida; Oliveira, Sónia; Rodrigues, Bernardo; Ferreira, João; Borges, Margarida; Miguel, LuísBackground: Triple-negative breast cancer accounts for 15% of all breast cancer cases, and it has a lower survival rate and higher incidence of early recurrence, particularly during the first 10 years after diagnosis. Objective: This study aimed to estimate the cost and burden of triple-negative breast cancer among the female population in 2019 in Portugal from a societal perspective. Methods: The prevalence of...
Evaluation of behavioral and neuroprotective effects of losartan in diabetic rats
Silva, Joana; Teixeira, Fábio; Esteves-Monteiro, Marisa; Araújo, Margarida; Magalhães, AnaDiabetes is known to negatively impact the brain, leading to memory loss and attention issues [1], as well as an increased incidence of depression, cognitive impairment, and behavioral changes. Recent studies indicate that angiotensin II AT1 receptor antagonists (ARAs) may reduce depressive symptoms, however, the mechanism of action is not yet fully understood [2]. The aim of the present study was to verify whe...