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Vasorelaxant activity and acute toxicity of the ethanolic extract of Zanthoxylu...

Silva, Joliane Carvalho; Azevedo, Pedro Simão da Silva; Souza, Fabiana de Moura; Aragão, Kalynca Kayla Viana; Sabino, Carla Kelly Barroso

The study evaluated the vasorelaxant effect induced by the ethanolic extract of the leaves of Zanthoxylum rhoifolium Lam (EEtOH-Zr/leaves). Wistar rats were treated with the leaf extract containing a single dose of 2,000 mg / kg, v.o. After 14 days, the animals were anesthetized for blood collection and subsequent analysis of the biochemical parameters; they were then euthanized (sodium pentobarbital-100 mg/kg,...

Date: 2019   |   Origin: Oasisbr
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