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Influence of the Particle Size on the Electrical, Magnetic and Biological Prope...

Regadas, Joana Soares; Gavinho, Sílvia Rodrigues; Teixeira, Sílvia Soreto; de Jesus, Juliana Vieira; Pádua, Ana Sofia; Silva, Jorge Carvalho

Bioglasses have been used throughout the past century as a biomaterial in the bone regeneration field. However, recent studies have attempted to use them as a therapeutic material as well, mainly in the treatment of osteosarcomas. The most widely recognized bioglass is the 45S5 Bioglass, invented by Larry Hench et al., which presents higher bioactivity. A possible application of this bioglass in the treatment o...


Biocomposite macrospheres based on strontium-bioactive glass for application as...

Oliveira, Ivone Regina de; Gonçalves, Isabela dos Santos; Wallace dos Santos, Kennedy; Lança, Maria Carmo; Vieira, Tânia; Silva, Jorge Carvalho

Traditional bioactive glass powders are typically composed of irregular particles that can be packed into dense configurations presenting low interconnectivity, which can limit bone ingrowth. The use of novel biocomposite sphere formulations comprising bioactive factors as bone fillers are most advantageous, as it simultaneously allows for packing the particles in a 3-dimensional manner to achieve an adequate i...


Extensive Investigation on the Effect of Niobium Insertion on the Physical and ...

Hammami, Imen; Gavinho, Sílvia Rodrigues; Pádua, Ana Sofia; Lança, Maria do Carmo; Borges, João Paulo; Silva, Jorge Carvalho; Sá-Nogueira, Isabel

Dental implants have emerged as one of the most consistent and predictable treatments in the oral surgery field. However, the placement of the implant is sometimes associated with bacterial infection leading to its loss. In this work, we intend to solve this problem through the development of a biomaterial for implant coatings based on 45S5 Bioglass® modified with different amounts of niobium pentoxide (Nb2O5)....


Antibacterial Biomaterial Based on Bioglass Modified with Copper for Implants C...

Hammami, Imen; Gavinho, Sílvia Rodrigues; Jakka, Suresh Kumar; Valente, Manuel Almeida; Graça, Manuel Pedro Fernandes; Pádua, Ana Sofia

Biofilm-related implant infections pose a substantial threat to patients, leading to inflammation in the surrounding tissue, and often resulting in implant loss and the necessity for additional surgeries. Overcoming this implantology challenge is crucial to ensure the success and durability of implants. This study shows the development of antibacterial materials for implant coatings by incorporating copper into...


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