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Ultrasonography Reliability in the Detection of Inflammatory and Structural Abn...
Brites, Luisa; Santiago, Mariana; Rovisco, João; Freitas, João; Silva, José A. P.; Silva, Inês; Teixeira, Filipa; Faria, Daniela S.; Silva, Cândida G.Background Ultrasonography is an image technique that allows rheumatologists to visualize structural and inflammatory changes within a joint. The objective of this study was to assess the interobserver and intraobserver reliability of musculoskeletal ultrasound (US) in the detection of inflammatory and destructive joint changes in patients with polyarthritis. Methods A Delphi exercise was undertaken to standard...
Effectiveness of non-pharmacological and non-surgical interventions on the impa...
Santos, Eduardo; Duarte, Cátia; Marques, Andréa; Cardoso, Daniela; Apóstolo, João; Silva, José A. P.; Barbieri-Figueiredo, MCReview question: The questions of this review are: i) What is the effectiveness of non-pharmacological and non-surgical interventions on pain, functional disability, fatigue, emotional wellbeing, sleep, coping and physical wellbeing of patients with rheumatoid arthritis (RA)? ii) What is the effectiveness of non-pharmacological and non-surgical interventions on the improvement of RA and quality of life for pati...
Tolerogenic versus inflammatory activity of peripheral blood monocytes and dend...
Carvalheiro, Tiago; Rodrigues, Ana; Lopes, Ana; Inês, Luís; Velada, Isabel; Ribeiro, Andreia; Martinho, António; Silva, José A. P.; Pais, Maria L.Abnormalities in monocytes and in peripheral blood dendritic cells (DC) subsets have been reported in systemic lupus erythematosus (SLE). We aim to clarify the tolerogenic or inflammatory role of these cells based on ICOSL or IFN-α and chemokine mRNA expression, respectively, after cell purification. The study included 18 SLE patients with active disease (ASLE), 25 with inactive disease (ISLE), and 30 healthy c...