Submitted by Diogo Mata (diogoxavier@direito.ufrj.br) on 2019-05-22T19:50:00Z No. of bitstreams: 1 JASilva.pdf: 609215 bytes, checksum: 416a81807b0fb2f4c885b48941090080 (MD5); Approved for entry into archive by Renata Souza (renatasouza@direito.ufrj.br) on 2019-05-31T15:07:38Z (GMT) No. of bitstreams: 1 JASilva.pdf: 609215 bytes, checksum: 416a81807b0fb2f4c885b48941090080 (MD5); Made available in DSpace on 2019...
This study aimed to obtain and characterize a microemulsion (ME) containing phenobarbital (PB). The PB was incorporated in the proportion of 5% and 10% in a microemulsion system containing Labrasol(r), ethanol, isopropyl myristate and purified water. The physicochemical characterization was performed and the primary stability of the ME was evaluated. An analytical method was developed using spectrophotometry in...