6 documents found, page 1 of 1
Toxicological findings about an anticancer fraction with casearins described by...
Pinheiro Fetreira, Paulo Michel; Santos, Denise Barbosa; Silva, Jurandy do Nascimento; Goudinho, Amanda Freitas; Silva Ramos, Carla LorenaMade available in DSpace on 2019-10-04T12:15:19Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-09-15; Fundacao de Amparo a Pesquisa do Estado do Piaui [FAPEPI]; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Ethnopharmacological relevance: Extracts, essential oils and molecules from Casearia sylvestris have popularly shown pharmacological actions against chronic diseases, as anxie...
Preclinical anticancer effectiveness of a fraction from Casearia sylvestris and...
Pinheiro Ferreira, Paulo Michel; Bezerra, Daniel Pereira; Silva, Jurandy do Nascimento; Costa, Marcilia Pinheiro da; Oliveira Ferreira, Jose Roberto deMade available in DSpace on 2018-11-27T16:55:43Z (GMT). No. of bitstreams: 0 Previous issue date: 2016-06-20; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Ethnopharmacological relevance: Casearia sylvestris (Salicaceae) is found in South America and presents antiulcerogenic, cytotoxic, antimicrobial, anti-inflammatory and antihypertensive activities. Aim of the study: To assess the in v...
Biomedical properties and potentiality of Lippia microphylla Cham. and its esse...
Simões, Evelyne Rolim Braun; Santos, Evelyne Alves; Abreu, Maria Carolina de; Silva, Jurandy do Nascimento; Nunes, Nárcia Mariana FonsecaLippia microphylla Cham. (Verbanaceae) is an endemic underexploited Brazilian vegetal. This work reviewed the biological potentialities of Lippia microphylla, emphasizing the properties of essential oils (EOs) and analyzed scientific indicators about genus Lippia and L. microphylla. Databases from 1948 to the present were searched and a software (Vantage Point 7.1) associated with Derwent Innovation Index was u...
Assessing chemical constituents of Mimosa caesalpiniifolia stem bark : possible...
Monção, Nayana Bruna Nery; Araújo, Bruno Quirino; Silva, Jurandy do Nascimento; Lima, Daisy Jereissati Barbosa; Ferreira, Paulo Michel PinheiroMimosa caesalpiniifolia is a native plant of the Brazilian northeast, and few studies have investigated its chemical composition and biological significance. This work describes the identification of the first chemical constituents in the ethanolic extract and fractions of M. caesalpiniifolia stem bark based on NMR, GC-qMS and HRMS analyses, as well as an assessment of their cytotoxic activity. GC-qMS analysis ...
Cytotoxic and toxicological effects of phthalimide derivatives on tumor and nor...
Ferreira, Paulo Michel Pinheiro; Costa, Patrícia Marçal da; Costa, Arinice de Menezes; Lima, Daisy Jereissati Barbosa; Drumond, Renata RosadoEleven phthalimide derivatives were evaluated with regards to their antiproliferative activity on tumor and normal cells and possible toxic effects. Cytotoxic analyses were performed against murine tumors (Sarcoma 180 and B-16/F-10 cells) and peripheral blood mononuclear cells (PBMC) using MTT and Alamar Blue assays. Following, the investigation of cytotoxicity was executed by flow cytometry analysis and antitu...
Teor de fenóis e flavonoides, atividades antioxidante e citotóxica das folhas, ...
Alves, Márcia de Jesus; Moura, Arkellau Kenned Silva; Costa, Luciana Muratori; Araújo, Éverton José Ferrreira de; Sousa, Gardene Maria deThe total phenol and flavonoid content, in addition to the antioxidant and cytotoxic activities, of extracts and fractions of Piptadenia moniliformis was determined. This honey plant species is commonly known as "catanduba" or "angico de bezerro". The aqueous fraction derived from the peels of the fruits exhibited the highest antioxidant activity, remaining comparable to the standard value, and there was a gene...