4 documents found, page 1 of 1
New pharmacological agents and novel cardiovascular pharmacotherapy strategies ...
Tamargo, Juan; Agewall, Stefan; Ambrosio, Giuseppe; Borghi, Claudio; Cerbai, Elisabetta; Dan, Gheorghe A; Drexel, Heinz; Ferdinandy, PéterDespite substantial advances in cardiovascular pharmacotherapy and devices in recent years, prevention and treatment of many cardiovascular diseases (CVDs) remain limited, thus reflecting the need for more effective and safer pharmacological strategies. In this review, we summarize the most relevant studies in cardiovascular pharmacotherapy in 2024, including the approval of first-in-class drugs for the treatme...
European Journal of Heart Failure consensus statement. Heart failure pharmacoth...
Luedde, Mark; Agewall, Stefan; Ambrosio, Giuseppe; Bayes‐Genis, Antoni; Borghi, Claudio; Cerbai, Elisabetta; Dan, Gheorghe A.; Drexel, HeinzHeart failure (HF) and atrial fibrillation (AF) are major global health challenges with rising prevalence and significant morbidity, mortality, and healthcare burden. Despite advances in HF management, AF remains a critical comorbidity that worsens outcomes and requires ad hoc treatment strategies, increasing the risk of non-adherence and side effects. While rhythm control strategies in AF have gained attention...
Perspectives on directions and priorities for future preclinical studies in reg...
Grigorian Shamagian, Lilian; Madonna, Rosalinda; Taylor, Doris; Climent, Andreu M.; Prosper, Felipe; Rosario, Luis; Bayes-Genis, AntoniThe myocardium consists of numerous cell types embedded in organized layers of ECM (extracellular matrix) and requires an intricate network of blood and lymphatic vessels and nerves to provide nutrients and electrical coupling to the cells. Although much of the focus has been on cardiomyocytes, these cells make up <40% of cells within a healthy adult heart. Therefore, repairing or regenerating cardiac tissue by...
European contribution to the study of ROS: A summary of the findings and prospe...
Egea, Javier; Fabregat, Isabel; Frapart, Yves M; Ghezzi, Pietro; Görlach, Agnes; Kietzmann, Thomas; Kubaichuk, Kateryna; Knaus, Ulla G.The European Cooperation in Science and Technology (COST) provides an ideal framework to establish multi-disciplinary research networks. COST Action BM1203 (EU-ROS) represents a consortium of researchers from different disciplines who are dedicated to providing new insights and tools for better understanding redox biology and medicine and, in the long run, to finding new therapeutic strategies to target dysregu...