2 documents found, page 1 of 1
Genetic homogeneity among Leishmania (Leishmania) infantum isolates from dog an...
Silva, Thais Almeida Marques da; Gomes, Luciana Inácia; Oliveira, Edward; Vital, Wendel Coura; Silva, Letícia de AzevedoBackground: Certain municipalities in the Belo Horizonte Metropolitan Area (BHMA), Minas Gerais, Brazil, have the highest human visceral leishmaniasis (VL) mortality rates in the country and also demonstrate high canine seropositivity. In Brazil, the etiologic agent of VL is Leishmania (Leishmania) infantum. The aim of this study was to evaluate the intraspecific genetic variability of parasites from humans and...
Susceptibility to re-infection in C57BL/6 mice with recombinant strains of Toxo...
Brandão, Geane Peroni; Melo, Maria Norma; Caetano, Bráulia Costa; Carneiro, Cláudia Martins; Silva, Letícia de Azevedo; Vitor, Ricardo Wagner de AlmeidaThis work reports results of re-infection of BALB/c and C57BL/6 mice with different recombinant strains of Toxoplasma gondii. Mice were prime-infected with the non-virulent D8 strain and challenged with virulent strains. PCR–RFLP of cS10-A6 genetic marker of T. gondii demonstrated that BALB/c mice were reinfected with the EGS strain, while C57BL/6 mice were re-infected with the EGS and CH3 strains. Levels of IF...