15 documents found, page 1 of 2

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Simultaneous quantitation of serum HBV DNA and HBeAg can distinguish between sl...

Silva, Luiz Caetano da; Nova, Maria Luiza da; Ono-Nita, Suzane Kioko; Pinho, João Renato Rebello; Sitnik, Roberta; Santos, Vera Aparecida dos

BACKGROUND: The quantitation of serum HBeAg is not commonly used to monitor viral response to therapy in chronic hepatitis B. METHODS: In this study, 21 patients receiving varying therapies were followed and their viral response monitored by concomitant viral load and HBeAg quantitation in order to study the meaning and the kinetics of both parameters. RESULTS: It was possible to distinguish between three diffe...

Date: 2009   |   Origin: Oasisbr



p53 immunostaining pattern in Brazilian patients with hepatocellular carcinoma

Alves, Venâncio Avancini Ferreira; Nita, Marcelo Eidi; Carrilho, Flair José; Ono-nita, Suzane Kioko; Wakamatsu, Alda; Lehrbach, Dárcio Matenhauer

Hepatocellular carcinoma (HCC) is an important type of cancer etiologically related to some viruses, chemical carcinogens and other host or environmental factors associated to chronic liver injury in humans. The tumor suppressor gene p53 is mutated in highly variable levels (0-52%) of HCC in different countries. OBJECTIVE: The objective of the present study was to compare the frequency of aberrant immunohistoch...

Date: 2004   |   Origin: Oasisbr

GB virus C/Hepatitis G virus and other putative hepatitis non A-E viruses

Pinho, João Renato Rebello; Silva, Luiz Caetano da

The identification of the major agents causing human hepatitis (Hepatitis A, B, C, D and E Viruses) was achieved during the last 30 years. These viruses are responsible for the vast majority of human viral hepatitis cases, but there are still some cases epidemiologically related to infectious agents without any evidence of infection with known virus, designated as hepatitis non A - E. Those cases are considered...

Date: 1996   |   Origin: Oasisbr

Avaliação da técnica de ELIEDA (enzyme-linked-immuno-electro-diffusion-assay) p...

Leal-Bacelar, Grace Mary; Kanamura, Hermínia Y.; Hoshino-Shimizu, Sumie; Lima, Dirce Mary C.; Abrantes-Lemos, Clarice P.; Silva, Luiz Caetano da

An immunoprecipitation technique, ELIEDA (enzyme-linked-immuno-electro-diffusion assay), was evaluated for the diagnosis of Schistosoma mansoni infection with low worm burden. One hundred of serum samples from patients excreting less than 600 eggs per gram of feces (epg), with unrelated diseases and clinically healthy subjects were studied. In patients with egg counts higher than 200 epg, the sensitivities of I...

Date: 1995   |   Origin: Oasisbr

Parasitological diagnosis of schistosomiasis mansoni: concomitant utilization o...

Lemos, Clarice P. Abrantes; Lima, Dirce Mary C.; Silva, Luiz Caetano da; Chieffi, Pedro Paulo

Date: 1995   |   Origin: Oasisbr

Antígenos polissacarídicos e proteicos circulantes de Schistosoma mansoni recon...

Costa-Cruz, Julia Maria; Hoshino-Shimizu, Sumie; Ferreira, Antonio Walter; Camargo, Mario E.; Brito, Thales de; Silva, Luiz Caetano da

Two sheep antisera, one of which raised against polysaccharide (Po) and other against protein (Pt) components of Schistosoma mansoni adult worms, were assessed by ELISA for their ability to detect circulating parasite antigens in patients with different clinical forms of chronic schistosomiasis mansoni. The former antiserum detected parasite antigens in liver granulomata and the latter in renal glomeruli from s...

Date: 1994   |   Origin: Oasisbr

Gelatin particle indirect agglutination test for serodiagnosis of schistosomias...

Kobayashi, Jun; Carrilho, Flair José; Shimabukuro, Tetsu; Silva, Luiz Caetano da; Soares, Elza Cotrim; Nishimura, Nancy Fusae; Chieffi, Pedro Paulo

A new serological test, the gelatin particle agglutination test (GPAT), was used for the serodiagnosis of schistosomiasis mansoni. This technique showed the sensitivity (90.6%) and specificity (97.8%) close to those of enzyme-linked immunosorbent assay. The GPAT can be easily and rapidly performed without specialized equipment, by using lyophilized antigen-coated gelatin particles. The test also seems to be use...

Date: 1994   |   Origin: Oasisbr

Active immunization against hepatitis B virus (HBV) with low-doses of plasma-de...

Carrilho, Flair José; Queiróz, Maria Lúcia; Fonseca, Luis Edmundo Pinto da; Obara, Leda; Silva, Luiz Caetano da

Date: 1991   |   Origin: Oasisbr

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