OBJECTIVE: To test whether swimming training benefits femoral neck strength in young diabetic rats under insulin therapy. METHODS: A total of 60 male Wistar rats (age: 40 days) were divided equally into the following six groups: control sedentary, control exercise, diabetic sedentary, diabetic exercise, diabetic sedentary plus insulin and diabetic exercise plus insulin. Diabetes was induced with a unique intrap...
Testar os efeitos de altas doses de cafeína na resistência óssea à fratura em ratas jovens submetidas a treinamento de saltos verticais. Ratas jovens foram alocadas em 4 grupos (Fatorial 2 x 2, Cafeína e Exercício). Grupos Cafeína receberam 3 doses (10 mg/100 g m.c.)/semana. Grupos Exercício realizaram treino de saltos verticais na água, 5 sessões/semana, por 6 semanas. Avaliou-se o cálcio urinário, diâmetro, m...
Experimental diabetes promotes contractile dysfunction in cardiomyocytes, but the effects of swimming in this disorder are not known. To test the effects of a swimming training program (STP) on cardiomyocyte contractile dysfunction in rats with experimental diabetes. Wistar rats (age: 30 days; mean body weight: 84.19 g) with diabetes induced by streptozotocin (60 mg/kg body weight; glucose > 300 mg/dl) were div...
Fundação de Amparo a Pesquisa do Estado de Minas Gerais; The Type 1 Diabetes Mellitus (T1DM) occurs due to decreased insulin secretion in the pancreas, which undertakes various organs. This disease is often associated with cardiac dysfunctions that characterize diabetic cardiomyopathy. The pharmacological treatment of T1DM is done by insulin and exercise has been used as a non-pharmacological strategy. The aim ...
Fundação de Amparo a Pesquisa do Estado de Minas Gerais; The aim of this study was to verify the effects of a swimming training (ST) on the morphological and mechanical properties of cardiac myocytes from different regions of the left ventricle (LV) of rats with experimental diabetes. One month old male Wistar rats (body mass ~ 250g) received an intraperitoneal injection of Streptozootocin (STZ, 60mg/kg body ma...
Background: The mechanisms responsible for the cardiac dysfunction associated with dietary protein restriction (PR) are poorly understood. Thus, this study was designed to evaluate the effects of PR on calcium kinetics, basal and β-adrenergic contractility in murine ventricular cardiomyocytes. Methods: After breastfeeding male Fisher rats were distributed into a control group (CG, n = 20) and a protein-restrict...