3 documents found, page 1 of 1
Hepatitis C in a Mobile Low-Threshold Methadone Program
Silva, Mário J; Pereira, Cláudia; Loureiro, Rafaela; Balsa, Catarina; Lopes, Paulo; Água-Doce, Ivone; Belo, Elsa; Martins, Helena C; Coutinho, RodrigoIntroduction: Data on the epidemiology of hepatitis C among individuals who use drugs in low-threshold settings are lacking, although crucial to assess the burden of disease and aid in the design of treatment strategies. Objective: The aim of this study was to characterize the epidemiology and disease related to hepatitis C in a population attending a low-threshold methadone program. Materials and methods: A cr...
Verification of Uncurated Protein Annotations
Rebholz-Schuhmann, Dietrich; Kirsch, Harald; Apweiler, Rolf; Camon, Evelyn; Dimmer, Emily; Lee, Vivian; Silva, Mário J; Couto, Francisco MMolecular Biology research projects produced vast amounts of data, part of which has been preserved in a variety of public databases. However, a large portion of the data contains a significant number of errors and therefore requires careful verification by curators, a painful and costly task, before being reliable enough to derive valid conclusions from it. On the other hand, research in biomedical information...
Mining the BioLiterature: towards automatic annotation of genes and proteins
Silva, Mário J; Couto, Francisco MThis chapter introduces the use of Text Mining in scientific literature for biological research, with a special focus on automatic gene and protein annotation. This field became recently a major topic in Bioinformatics, motivated by the opportunity brought by tapping the BioLiterature with automatic text processing software. The chapter describes the main approaches adopted and analyzes systems that have been d...