Introduction: Sporadic Creutzfeldt-Jakob disease (sCJD) is the most frequent of human prion diseases, with an estimated incidence of 1 case per million / habitants per year. Clinical manifestations include multidomain cognitive impairment with pyramidal, extrapyramidal and/or cerebellar signs. It is a rapidly progressive and fatal disease. Our aim was to do a sociodemographic, clinical and progression evaluatio...
Introdução: O carcinoma do recto localmente avançado (CRLA) é habitualmente tratado com Radioterapia (RT) seguida por Cirurgia. Existem dois esquemas possíveis para irradiação neoadjuvante: o longo (EL), associado a quimioterapia (QT), e o curto (EC). Objectivos: Comparar resposta e toxicidade à terapêutica com EL e EC em doentes com CRLA. Material e Métodos: Foram incluídos doentes com CRLA tratados de 2002 a ...
Natural resources and physical cultural resources, referred to in this paper as “Environmental Resources”, can be important assets for regional competitiveness and innovation. In recent years, these types of assets have been increasingly taken into consideration in the design and implementation of regional development strategies, as a consequence of their potential role as a source of differentiation and of new...
.; A sífilis é uma doença sistémica crónica sexualmente transmissível. O envolvimento gástrico é pouco frequente. Os autores apresentam um doente de 35 anos, com epigastralgias, náuseas, vómitos e com o diagnóstico inicial de carcinoma gástrico. Esta patologia é de difícil diagnóstico, sem sintomatologia patognomónica e cujas biópsias endoscópicas são semelhantes a adenocarcinoma ou linfoma. Palavra-chave: Sífi...
Background: The genetic contribution to stroke is well established but it has proven difficult to identify the genes and the disease-associated alleles mediating this effect, possibly because only nuclear genes have been intensely investigated so far. Mitochondrial DNA (mtDNA) has been implicated in several disorders having stroke as one of its clinical manifestations. The aim of this case-control study was to ...
ln Hodgkin's disease, the anatomical extension of the disease and the histological sub type are the major determinants of the forms of disease presentation. Frequently, clinical manifestations have low specificity and it is difficult to suspect tbe diagnosis. A clinical case is reported of abdominal Hodgkin's disease of tbe lympbocyte depleted type, that presented initially with pyrexia of unknown origin, ...
Cardiac tamponade is a serious, potentially fatai situation if not promptly treated. We recognised the seriousness of this situation in our clinical practice and so far we present a casuistry study of the cases admitted in the /CU of Hospital de Curry Cabral from 1983 to 1993.; O tamponamento cardíaco é uma situação que, se não resolvida prontamente, pode conduzir à morte. Foi o contacto com a gravidade desta...