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Creutzfeldt-Jakob Disease: A Decade of Assistential Activity at Centro Hospital...

Marques, Ana João; Mendes, Michel; Carvalho, Andreia; Almendra, Ricardo; Matas, Andreia; Veiga, Andreia; Guimarães, Pedro; Velon, Ana Graça

Introduction: Sporadic Creutzfeldt-Jakob disease (sCJD) is the most frequent of human prion diseases, with an estimated incidence of 1 case per million / habitants per year. Clinical manifestations include multidomain cognitive impairment with pyramidal, extrapyramidal and/or cerebellar signs. It is a rapidly progressive and fatal disease. Our aim was to do a sociodemographic, clinical and progression evaluatio...

Date: 2024   |   Origin: SINAPSE

Radioterapia neoadjuvante no carcinoma do recto: resposta à terapêutica e sua t...

Casalta-Lopes, João; Nobre-Góis, Inês; Teixeira, Tânia; Silva, Mário Rui; Sá, Anabela; Borrego, Margarida; Soares, Paula

Introdução: O carcinoma do recto localmente avançado (CRLA) é habitualmente tratado com Radioterapia (RT) seguida por Cirurgia. Existem dois esquemas possíveis para irradiação neoadjuvante: o longo (EL), associado a quimioterapia (QT), e o curto (EC). Objectivos: Comparar resposta e toxicidade à terapêutica com EL e EC em doentes com CRLA. Material e Métodos: Foram incluídos doentes com CRLA tratados de 2002 a ...

Date: 2015   |   Origin: Revista Portuguesa de Cirurgia

Cerebellar metastasis as a unique presenting feature of linitis-plastica: a ver...

Velon, Ana Graça; Guimarães, Pedro; Carvalho, Dina; Silva, Mário Rui


Environment based innovation: policy questions

Pessoa, Argentino; Silva, Mário Rui

Natural resources and physical cultural resources, referred to in this paper as “Environmental Resources”, can be important assets for regional competitiveness and innovation. In recent years, these types of assets have been increasingly taken into consideration in the design and implementation of regional development strategies, as a consequence of their potential role as a source of differentiation and of new...

Date: 2009   |   Origin: Revista Finisterra

Gastric Syphilis: Differential diagnosis with Gastric Carcinoma – A case report

Bento, Ana Sofia; Baptista, Hamilton Neves; Silva, Mário Rui; Oliveira, Fernando José Serra; Martinho, Fernando Jaime

.; A sífilis é uma doença sistémica crónica sexualmente transmissível. O envolvimento gástrico é pouco frequente. Os autores apresentam um doente de 35 anos, com epigastralgias, náuseas, vómitos e com o diagnóstico inicial de carcinoma gástrico. Esta patologia é de difícil diagnóstico, sem sintomatologia patognomónica e cujas biópsias endoscópicas são semelhantes a adenocarcinoma ou linfoma. Palavra-chave: Sífi...

Date: 2009   |   Origin: Revista Portuguesa de Cirurgia

Mitochondrial haplogroup H1 is protective for ischemic stroke in portuguese pat...

Rosa, Alexandra; Fonseca, Benedita V.; Krug, Tiago; Manso, Helena; Gouveia, Liliana; Albergaria, Isabel; Gaspar, Gisela; Correia, Manuel

Background: The genetic contribution to stroke is well established but it has proven difficult to identify the genes and the disease-associated alleles mediating this effect, possibly because only nuclear genes have been intensely investigated so far. Mitochondrial DNA (mtDNA) has been implicated in several disorders having stroke as one of its clinical manifestations. The aim of this case-control study was to ...


Hodgkin's disease presenting with pyrexia of unknown origin

Branco, Vitor; Salvador, Maria João; Silva, Mário Rui; Martins, Paulo; Carvalho, Armando; Almiro, Eurico; Porto, Armando

ln Hodgkin's disease, the anatomical exten­sion of the disease and the histological sub­ type are the major determinants of the forms of disease presentation. Frequently, clinical ma­nifestations have low specificity and it is diffi­cult to suspect tbe diagnosis. A clinical case is reported of abdominal Hodgkin's disease of tbe lympbocyte depleted type, that presented initi­ally with pyrexia of unknown origin, ...


Derrame pericárdico e tamponamento cardíaco - Casuística da UCI do Hospital de ...

Zita Veiga, Manuela; Silva, Mário Rui; Palmeiro Ribeiro, J.; Guimarães, Rui; Oliveira, Judite; Mota, Castel-Branco

Cardiac tamponade is a serious, potentially fatai situation if not promptly treated. We recognised the seriousness of this situation in our clinical practi­ce and so far we present a casuistry study of the cases admitted in the /CU of Hospital de Curry Ca­bral from 1983 to 1993.; O tamponamento cardíaco é uma situação que, se não resolvida prontamente, pode conduzir à morte. Foi o contacto com a gravidade desta...


Industrialisation diffuse et developpement

Pecqueur, Bernard; Silva, Mário Rui


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