Humane endpoints are increasingly being used in animal experiments to ensure compliance with ethical regulations, namely the 3Rs policy. This study aimed to develop a clear humane endpoint (HE) scoring system for a streptozotocin (STZ)-induced diabetes model in male Sprague-Dawley rats. The rats were divided into a control (n=8) and an induced (n=16) group, with the latter receiving 10% fructose in their drinki...
austino-Rocha AI, Silva-Reis R, Silva J, Valada A, Azevedo T, Anjos L, Silva MAS, Cardoso SM, Oliveira PA. 2023. Animal welfare in diabetes research: a humane endpoint scoring system. 3rd International Conference on Diabetes, Endocrinology & Obesity, 20 a 21 de março.
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