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Klotho in cancer: potential diagnostic and prognostic applications

Mota, J; Lima, AMM; Souza de Andrade, M; Brito, HO; Silva, MMAL; Faustino-Rocha, Ana; Oliveira, PA; Lopes, FF; Gil da Costa, Rui

Klotho proteins, αKlotho, βKlotho, and γKlotho, exert tumor-suppressive activities via the fibroblast growth factor receptors and multiple cell-signaling pathways. There is a growing interest in Klotho proteins as potential diagnostic and prognostic biomarkers for multiple diseases. However, recent advances regarding their roles and potential applications in cancer remain disperse and require an integrated anal...

Date: 2024   |   Origin: Repositório Científico da Universidade de Évora
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