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Correction: Diniz et al. Silver Nanoparticles-Composing Alginate/Gelatine Hydro...

Diniz, Flavia Resende; Maia, Romerito Cesar A. P.; de Andrade, Lucas Rannier M.; Andrade, Luciana Nalone; Vinicius Chaud, Marco

In the original publication, there was a mistake in Figure 6 as published [...]


Silver nanoparticles-composing alginate/gelatine hydrogel improves wound healin...

Diniz, Flavia Resende; Maia, Romerito Cesar A. P.; Andrade, Lucas Rannier; Andrade, Luciana Nalone; Vinicius Chaud, Marco; Silva, Classius Ferreira da

Polymer hydrogels have been suggested as dressing materials for the treatment of cutaneous wounds and tissue revitalization. In this work, we report the development of a hydrogel composed of natural polymers (sodium alginate and gelatin) and silver nanoparticles (AgNPs) with recognized antimicrobial activity for healing cutaneous lesions. For the development of the hydrogel, different ratios of sodium alginate ...


Praziquantel-loaded solid lipid nanoparticles: Production, physicochemical char...

Andrade, Luciana Nalone; Marques, Conrado; Barbosa, Thallysson; Santos, Rafael; Chaud, Marco Vinícius; Ferreira da Silva, Classius

Praziquantel (PZQ) is an anthelmintic drug, being the first choice for the treatment of schistosomiasis. Its high hydrophobic character and its low water solubility are the main limitations to the development of liquid formulations for the oral administration of the drug. The aim of this work was to develop Solid Lipid Nanoparticles (SLN) for the loading of PZQ for the treatment of S. mansoni infections. PZQ-SL...


Derivados p-Mentânicos : estudos de relação estrutura-atividade e avaliação de ...

Andrade, Luciana Nalone

Cancer is a disease of high incidence, high mortality and difficult to treat, and there is therefore a constant social interest in the search for more effective therapies. In this sense, essential oils and their constituents are promising source of natural products as antitumor substances. Thus, the aim of this study was to evaluate the cytotoxic activity of 19 p-menthane derivatives structurally correlated wit...

Date: 2019   |   Origin: Oasisbr

Evaluation of the cytotoxicity of structurally correlated p-menthane derivatives

Andrade, Luciana Nalone; Lima, Tamires Cardoso; Amaral, Ricardo Guimarães; Pessoa, Cláudia do Ó; Moraes Filho, Manoel Odorico de; Soares, Bruno Marques

Compounds isolated from essential oils play an important role in the prevention and treatment of cancer. Monoterpenes are natural products, and the principal constituents of many essential oils. The aim of this study was to investigate the cytotoxic potential of p-menthane derivatives. Additionally, analogues of perillyl alcohol, a monoterpene with known anticancer activity, were evaluated to identify the molec...

Date: 2016   |   Origin: Oasisbr

Anti-ulcer activity of essential oil constituents

Oliveira, Francisco de Assis; Andrade, Luciana Nalone; Sousa, Élida Batista Vieira de; Sousa, Damião Pergentino de

Essential oils have attracted considerable worldwide attention over the last few decades. These natural products have wide-ranging pharmacological activities and biotechnological applications. Faced with the need to find new anti-ulcer agents and the great effort on the development of drugs for the treatment of ulcers, in this review, the antiulcer activities of 21 bioactive compounds found in essential oils ar...

Date: 2014   |   Origin: Oasisbr

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