Hoodia gordonii is a plant species used traditionally in southern Africa to suppress appetite. Recently, it has been associated with a significant increase in blood pressure and pulse rate in women, suggesting sympathomimetic activity. The present study investigated the possible antidepressant-like effects of acute and repeated (15 days) administration of H. gordonii extract (25 and 50 mg/kg, po) to mice expose...
Riparin II (RipII), an alkamide isolated from the green fruit of Aniba riparia, was tested in the various animal models of inflammation to investigate its anti-inflammatory activity. Male Wistar rats (180–240 g) were treated with RipII by gavage at doses 25 or 50 mg/kg, before initiating the inflammatory responses. The tests used were paw edema induced by carrageenan, dextran, histamine or serotonin; peritoniti...
Um estudo transversal sobre a utilização de medicamentos fitoterápicos nas Unidades Básicas de Atenção à Saúde da Família (UBASF) do município de Maracanaú-Ce foi realizado em duas etapas entre agosto de 2002 e janeiro de 2003; Primeiramente, foram entrevistados nas farmácias das UBASF, mediante questionário estruturado, 226 usuários maiores de 18 anos, com prescrição contendo medicamento fitoterápico; e poster...
Isopulegol is a monoterpene alcohol present in the essential oils of various plants, and has been used in the manufacture of fragrances with blossom compositions. In order to investigate its effects on animal models of CNS actions, isopulegol was administered to male Swiss mice at single doses of 25 and 50 mg/kg 30 (i.p.) or 60 min (p.o.) before the experiments. Control animals received vehicle (saline 0.9% in ...