491 documents found, page 1 of 50

Monitoring the Mental Health of Portuguese University Students: Insights from T...

Objective: To assess the prevalence of depressive and anxiety symptoms in university students across three academic years and the factors contributing to these symptoms. Methods: A repeated cross-sectional study was conducted using independent samples each academic year. An online questionnaire was administered to students from seven higher education institutions during the academic years 2022/2023, 2023/2024, ...

A regulatory perspective on the applicability of NAMs in genotoxicity and carci...

New Approach Methodologies (NAMs) are gaining significant momentum globally to reduce animal testing and enhance the efficiency and human relevance of chemical safety assessment. Even with substantial EU commitment from regulatory agencies and the academic community, the full regulatory adoption of NAMs remains a distant prospect. This challenge is further complicated by the fact that the academic world, orient...

Shaping the future of human biomonitoring (HBM)

Human biomonitoring (HBM) continues to play an indispensable role within exposure science, offering insights into aggregate chemical exposures across populations and life stages. Since 2018, the European chapter of the International Society of Exposure Science Human Biomonitoring Working Group (ISES Europe HBM WG) has aimed to facilitate generation of more and high-quality HBM data. The working group aims to st...

Promoção do insight e da gestão do regime terapêutico na pessoa com esquizofrenia

O ensaio do micronúcleo em células da mucosa bucal: aplicabilidade em biomonito...

As exposições ambientais e ocupacionais a alguns agentes químicos ou físicos representam sérios riscos para a saúde humana. A biomonitorização humana (BMH) permite quantificar a exposição a substâncias químicas e seus efeitos precoces através da caracterização de biomarcadores de exposição e de biomarcadores de efeito. O ensaio do micronúcleo em células bucais (MNBMCyt) é um biomarcador precoce de genotoxicidad...

HBM4EU chromates study: the Portuguese integrated and harmonized study on expos...

In the scope of the European Union (EU) human biomonitoring initiative, a multicentric study on different occupational settings from several European countries was performed, to provide information on occupational exposure to hexavalent chromium [Cr(VI)], a known lung carcinogen. Biomonitoring approaches were used to obtain exposure data to support the implementation of new risk management measures and policy a...

Microalgae biomass–A source of sustainable dietary bioactive compounds towards ...

Microalgae are recognized as a promising plant-based protein source and are rich in bioactive compounds with potential health benefits. This review explores the role of microalgae bioactive compounds in global health, analysing findings from animal studies and human trials and their possible impact on health. It highlights the bioactive properties of microalgae, which enhance oral, cardiovascular, brain, gastro...

Biomonitorização humana e genotoxicidade ambiental: quatro décadas de investiga...

A regulatory perspective on the applicability of NAMs in genotoxicity and carci...

New Approach Methodologies (NAMs) are gaining significant momentum globally to reduce animal testing and enhance the efficiency and human relevance of chemical safety assessment. Even with substantial EU commitment from regulatory agencies and the academic community, the full regulatory adoption of NAMs remains a distant prospect. This challenge is further complicated by the fact that the academic world, orient...

Shaping the future of human biomonitoring (HBM): progress, strategy, and global...

Human biomonitoring (HBM) continues to play an indispensable role within exposure science, offering insights into aggregate chemical exposures across populations and life stages. Since 2018, the European chapter of the International Society of Exposure Science Human Biomonitoring Working Group (ISES Europe HBM WG) has aimed to facilitate generation of more and high-quality HBM data. The working group aims to st...