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Design and development of gemcitabine-loaded nanoplatforms for advanced pancrea...

Silva, Miguel Pereira da

Tese de Doutoramento em Ciências Farmacêuticas apresentada à Faculdade de Farmácia; Pancreatic cancer (PC) is currently one of the most challenging human malignancies worldwide with its incidence and mortality projected to rise in the next years. The lack of early diagnosis, together with poor prognosis, high rate of tumor relapse and pathological complexity vastly undermine its therapy success and patient surv...


Naringenin Nano-Delivery Systems and Their Therapeutic Applications

Bhia, Mohammed; Motallebi, Mahzad; Abadi, Banafshe; Zarepour, Atefeh; Silva, Miguel Pereira da; Saremnejad, Farinaz; Santos, Ana Cláudia; Zarrabi, Ali

Naringenin (NRG) is a polyphenolic phytochemical belonging to the class of flavanones and is widely distributed in citrus fruits and some other fruits such as bergamot, tomatoes, cocoa, and cherries. NRG presents several interesting pharmacological properties, such as anti-cancer, anti-oxidant, and anti-inflammatory activities. However, the therapeutic potential of NRG is hampered due to its hydrophobic nature,...


Topical Minoxidil-Loaded Nanotechnology Strategies for Alopecia

Santos, Ana Cláudia; Silva, Miguel Pereira da; Guerra, Catarina; Costa, Diana; Peixoto, Diana; Pereira, Irina; Pita, Inês R.; Ribeiro, António J.

Androgenetic alopecia (AGA) is a multifactorial and age-related condition characterized by substantial hair loss a ecting both men and women. Conventional treatments include the use of topical minoxidil (MNX) formulations to stimulate hair growth and restore hair condition. However, those treatments are associated with limited performance and a lack of tolerability and compliance due to the emergence of adverse...


Evolution of Hair Treatment and Care: Prospects of Nanotube-Based Formulations

Santos, Ana Cláudia; Panchal, Abhishek; Rahman, Naureen; Silva, Miguel Pereira da; Pereira, Irina; Veiga, Francisco; Lvov, Yuri

A new approach for hair treatment through coating with nanotubes loaded with drugs or dyes for coloring is suggested. This coating is produced by nanotube self-assembly, resulting in stable 2-3 µm thick layers. For medical treatment such formulations allow for sustained long-lasting drug delivery directly on the hair surface, also enhanced in the cuticle openings. For coloring, this process allows avoiding a di...


Relatórios de Estágio e Monografia intitulada “O Parkinson, a Microbiota Intest...

Silva, Miguel Pereira da

Relatório de Estágio do Mestrado Integrado em Ciências Farmacêuticas apresentado à Faculdade de Farmácia; Nas seguintes páginas, apresentarei os meus dois relatórios de estágio: em Farmácia Hospitalar e em Farmácia Comunitária. Descreverei o meu percurso e as minhas aprendizagens, assim como o trabalho desenvolvido por mim, e, posteriormente, apresentarei a minha dissertação relativa ao tema “O Parkinson, a Mic...


Ideais de civilidade : os manuais de etiqueta e o disciplinamento dos comportam...

Silva, Miguel Pereira da

The analysis of the manuals of etiquette in the |new| social settings was the research object of the present study, specifically, with regard to forms of discipline of behavior in contemporary society. We assumed that the speeches contained in these manuals of etiquette generate senses and meanings among the social groups producing interchangeable roles in manners and behaviors of individuals who supposedly coe...

Data: 2017   |   Origem: Oasisbr

A reconstrução psicossocial da identidade religiosa: um estudo dos conversos à ...

Silva, Miguel Pereira da

Cette étude vise à examiner la reconstruction de l'identité religieuse, à partir d'une étude du processus de conversion à l'Eglise Universelle du Royaume de Dieu, en se concentrant sur les facteurs psychosociaux comme facteurs de déclenchement des crises d'identité et, partant, sa restructuration par la rencontre avec toute la vérité universelle sur l'Eglise néopentecôtiste, à la fois par l'intermédiaire de son...

Data: 2015   |   Origem: Oasisbr

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