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Metabolic acidosis aggravates experimental acute kidney injury

Magalhães, Patrícia Andréa da Fonseca; Brito, Teresinha Silva de; Freire, Rosemayre Souza; Silva, Moisés Tolentino Bento da; Santos, Armênio Aguiar dos

ims Ischemia/reperfusion (I/R) injury and metabolic acidosis (MA) are two critical conditions that may simultaneously occur in clinical practice. The result of this combination can be harmful to the kidneys, but this issue has not been thoroughly investigated. The present study evaluated the influence of low systemic pH on various parameters of kidney function in rats that were subjected to an experimental mode...

Date: 2016   |   Origin: Oasisbr

Exercícios físicos de alta intensidade agudo e crônico inibem o esvaziamento gá...

Silva, Moisés Tolentino Bento da

In the recent years, there is a general consensus on the benefits of regular physical activity on health caliber, prevention and treatment of various chronic diseases besides improving general quality of life. Specifically, physical activity of varied intensities broadly influence vital physiological systems involving the neuromuscular system (promoting increased muscle strength and mass) cardiovascular (induc...

Date: 2013   |   Origin: Oasisbr

Atrial stretch delays gastric emptying of liquids in awake rats

Palheta Júnior, Raimundo Campos; Silva, Moisés Tolentino Bento da; Barbosa, H. L. G.; Pinheiro, Ana Débora Nunes; Cardoso, KKátia Virgínia Viana

Aims: We previously reported that mechanical atrial stretch (AS) by balloon distention increased gastric tonus in anesthetized rats. The present study evaluated the effect of AS on the gastric emptying of a liquid test meal in awake rats and its underlying neural mechanisms. Main methods: Anesthetizedmale rats received a balloon catheter into the right atrium and a gastrostomy cannula. The next day,mean arteria...

Date: 2013   |   Origin: Oasisbr

Linalool-rich rosewood oil induces vago-vagal bradycardic and depressor reflex ...

Siqueira, Rodrigo José de; Rodrigues, Karilane Maria Silvino; Silva, Moisés Tolentino Bento da; Correia Junior, Carlos Antônio Barros

Cardiovascular effects of the linalool-rich essential oil of Aniba rosaeodora (here named as EOAR) in normotensive rats were investigated. In anesthetized rats, intravenous (i.v.) injection of EOAR induced dosedependent biphasic hypotension and bradycardia. Emphasis was given to the first phase (phase 1) of the cardiovascular effects, which is rapid (onset time of 1–3 s) and not observed in animals submitted to...

Date: 2013   |   Origin: Oasisbr

Preconditioning with a novel metallopharmaceutical NO donor in anesthetized rat...

Oriá, Reinaldo Barreto; Lopes, Luiz Gonzaga de França; Brito, Gerly Anne de Castro; Santos, Armenio Aguiar dos; Vasconcelos, Raquel Cavalcante de

Rut-bpy is a novel nitrosyl–ruthenium complex releasing NO into the vascular system. We evaluated the effect of Rut-bpy (100 mg/kg) on a rat model of brain stroke. Forty rats were assigned to four groups (Saline solution [SS], Rut-bpy, SS?ischemia–reperfusion [SS?I/ R] and Rut-bpy?ischemia–reperfusion [Rut-bpy?I/R]) with their mean arterial pressure (MAP) continuously monitored. The groups were submitted (SS?I/...

Date: 2013   |   Origin: Oasisbr

Talking about bioelectrical potentials using rings of the mesenteric artery wit...

Ribeiro-Filho, Helder Veras; Brito, Teresinha Silva de; Lima, F. J. B.; Pinho, J. P. M.; Sousa, D. F.; Silva, Moisés Tolentino Bento da

In the present study, a practical activity is proposed to adopt an experimental approach to demonstrate the relationship between the equilibrium potential for K and transmembrane electrical potential without glass micropipettes. A conventional setup for recording contractile activity of isolated smooth muscle preparations was used based on the events elegantly described by Somlyo and Somlyo in the 1960s. They s...

Date: 2013   |   Origin: Oasisbr

Effects of administering testosterone undecanoate in rats subjected to physical...

Silva, Moisés Tolentino Bento da; Martins, Maria do Carmo de Carvalho e; Torres-Leal, Francisco Leonardo; Barros, Talvany Luiz

The aim of the work was evaluate the effects of testosterone undecanoate (TU) treatment combined with moderate physical training on: the estrous cycle, body weight (BW), motor behavior (MB), and the morphohistology of the reproductive system, the liver and kidney in rats. Female Wistar rats (180 g - 250 g) were divided as follows: sedentary + TU (S + TU), trained + TU (T + TU), sedentary + vehicle (S + V), trai...

Date: 2013   |   Origin: Oasisbr

Efeito da prática de capoeira sobre os parâmetros cardiovasculares

Maia, Rodrigo Batista; Martins, Maria do Carmo de Carvalho e; Rocha, Cláudio Henrique Lima; Ricarte, Irapuá Ferreira; Silva, Vítor Brito da

Background : Evaluations of cardiovascular alterations caused by fighting sports are extremely important, as there are no concise data in the literature. Objective : To evaluate and compare hemodynamic and anthropometric alterations among individuals engaged in capoeira (Brazil’s balletic martial art) and sedentary individuals. Methods : The BMI and body composition were evaluated for capoeira athletes (n=15) a...

Date: 2013   |   Origin: Oasisbr

A sobrecarga aguda cardíaca advinda de fístula aorto-caval retarda o esvaziamen...

Silva, Moisés Tolentino Bento da

In view that the behaviour of gastrointestinal tract seems to have intimate relationship with the activity of the cardiovascular system, we decided to verify whether the redistribution of blood volume through fistula aorto-caval with sizes of needles (21, 23 or 26G) affect the motility of the gastrointestinal tract in rats awaked. Male albino rats (230 to 280g) were divided into groups false-operated (FO) or de...

Date: 2012   |   Origin: Oasisbr

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