Sporotrichosis is a subacute or chronic subcutaneous infection, caused by the fungus Sporothrix schenkii complex, occurring in human and animal tissues. Potassium iodide and itraconazole have been used as effective therapy for first-choice treatment, while am- photericin B may be indicated for disseminated infection. However, the adverse effects of potassium iodide and amphotericin B or the long duration of the...
The present study evaluated the maintenance of Sporothrix spp. (6 Sporothrix brasiliensis;6S. schenckii;5 S. mexicana, and 3 S. globosa) in saline at 4 C, and in 10% glycerol plus either 10% lactose or 10% sucrose, at -20 C and -80 C. Viability was assessed after 3, 6, and 9 months of storage, through the recovery of strains on potato dextrose agar and analysis of macro- and micromorphological features. Conidiu...
Sporotrichosis is a subcutaneous mycosis that affects humans and animals caused by the dimorphic fungi of the genus Sporothrix. The storage of such microorganisms in culture collections is necessary to monitor the strains of Sporothrix spp. over the years. Despite the existence of effective antifungal therapies against this disease the search for new drugs for the treatment is necessary. Compounds such as farne...