The aim of this study was to analyse the acceptance of technology by professors and the adherence of dental students to virtual teaching during the social distancing period due to the coronavirus disease (COVID-19) pandemic. This was a retrospective observational cross-sectional study that involved the anonymous opinion of dental school professors. After each virtual class, the professors filled out the e-quest...
OBJECTIVES: Characterize the cell profile and immunostaining of proinflammatory markers in an experimental model of bisphosphonate-related osteonecrosis of the jaw (BRONJ). MATERIALS AND METHODS: Male Wistar rats (n = 6-7) were treated chronically with saline solution or zoledronic acid (ZA) at 0.04, 0.20, and 1.00 mg kg(-1) (1.4 × 10(-7) , 6.9 × 10(-6) , and 3.4 × 10(-5) mol kg(-1) ), and subsequently, the fir...
Abstract Immune cell profile of dental pulp tissue treated with zoledronic acid. International Endodontic Journal. Aim To characterize the pulp immune cell profile in the teeth of rats treated with zoledronic acid (ZA). Methodology Male Wistar rats (n = 6 per group) received four intravenous infusions of ZA at doses of 0.04, 0.20 or 1.00 mg kg 1 ZA or saline (control). On the 70th experimental day, they were euth...
OBJECTIVES: To evaluate the expression of p-AKT, p-JNK, FoxO3a and KI-67 in samples of Oral Squamous Cell Carcinoma (OSCC) and Oral Epithelial Dysplasias (OEDs) to understand their possible involvement in the malignant transformation process of oral lesions. MATERIALS AND METHODS: Tissue samples of 20 cases of OSCCs, 20 OEDs and normal oral mucosa were subjected to immunohistochemistry reactions for anti-p-Akt,...
Abstract: The mortality rate associated with oral cancer is estimated at approximately 12,300 deaths per year, and the survival rate is only 40% to 50% for diagnosed patients and is closely related to the duration of time between disease perception and its diagnosis and treatment. Socioeconomic risk factors are determinants of the incidence and mortality related to oral cancer. We conducted a retrospective, cro...
The Aneurysmal Bone Cyst (ABC) is an expansive osteolytic, radiolucent, multilocular, eccentric lesion of unknown origin consisting of spaces filled with blood in any segment of the skeleton, being most frequently encountered in the diaphysis of the long bones or the spinal cord. It may occur as distinct clinico-pathological entity or as pathophysiological alteration of a preexisting lesion, like giant-cells le...
Abstract: Structural deficiencies and functional abnormalities of heart valves represent an important cause of cardiovascular morbidity and mortality, and a number of diseases, such as aortic stenosis, have been recently associated with infectious agents. This study aimed to analyze oral bacteria in dental plaque, saliva, and cardiac valves of patients with cardiovascular disease. Samples of supragingival plaqu...
Introduction Oral anticoagulants are widely prescribed drugs. Interruption of anticoagulant therapy prior to oral surgery has been an issue of great controversy. The purpose of this study was to evaluate the incidence of bleeding complications after dental extractions in patients on anticoagulant therapy (warfarin) in whom different local hemostatic methods were used. Material and methods Patients using warfari...
Aim: To present the clinical findings of a patient with Fibrodysplasia Ossificans Progressiva (FOP), highlighting peculiarities of dental treatment in patients with this condition. Background: FOP is a rare genetic disease characterized by skeletal malformations and ectopic ossifications in skeletal muscles, tendons, ligaments and aponeurosis. Exacerbation of these ossifications can be caused by dental treatmen...
The aim of this study is to share the experience of implementing a network for the diagnosis of oral cancer by integrating primary, secondary, and tertiary oral health care centers and identifying the possible weaknesses of the process. The study also investigated the risks of exposure to the main risk factors for oral and lip cancer and their most common potentially malignant lesions (PML). A quantitative cros...