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What lessons can we learn? Clinical and epidemiological retrospective analysis ...

Criado,Roberta Fachini Jardim; Criado,Paulo Ricardo; Baldavira,Nathalia; Cardial,Debora; Gimenez-Arnau,Ana Maria; Machado Filho,Carlos D’Apparecida

Abstract Background: There are few epidemiological studies of urticaria, published in the indexed literature (PubMed/Medline). Objective: The study aimed to evaluate the epidemiological and clinical data among patients with urticaria/angioedema attending a reference clinic in Brazil. Methods: Two hundred sixty-seven patients were evaluated retrospectively considering demographic data, time course of the disease...

Data: 2021   |   Origem: Oasisbr

Update on vasculitis: an overview and dermatological clues for clinical and his...

Morita,Thâmara Cristiane Alves Batista; Trés,Gabriela Franco S.; Criado,Roberta Fachini Jardim; Sotto,Mirian Nacagami; Criado,Paulo Ricardo

Abstract The term vasculitis refers to the inflammation of vessel walls. It may range in severity from a self-limited disorder in one single organ to a life-threatening disease due to multiple organ failure. It has many causes, although they result in only a few histological patterns of vascular inflammation. Vessels of any type and in any organ can be affected, a fact that results in a broad variety of signs a...

Data: 2020   |   Origem: Oasisbr

Update on vasculitis: overview and relevant dermatological aspects for the clin...

Morita,Thâmara Cristiane Alves Batista; Criado,Paulo Ricardo; Criado,Roberta Fachini Jardim; Trés,Gabriela Franco S.; Sotto,Mirian Nacagami

Abstract Vasculitis is a group of several clinical conditions in which the main histopathological finding is fibrinoid necrosis in the walls of blood vessels. This article assesses the main dermatological aspects relevant to the clinical and laboratory diagnosis of small- and medium-vessel cutaneous and systemic vasculitis syndromes. The most important aspects of treatment are also discussed.

Data: 2020   |   Origem: Oasisbr

Consensus on the diagnostic and therapeutic management of chronic spontaneous u...

Criado,Paulo Ricardo; Maruta,Celina Wakisaka; Alchorne,Alice de Oliveira de Avelar; Ramos,Andréa Machado Coelho; Gontijo,Bernardo

Abstract: Background: Urticarias are frequent diseases, with 15% to 20% of the population presenting at least one acute episode in their lifetime. Urticaria are classified in acute ( ≤ 6 weeks) or chronic (> 6 weeks). They may be induced or spontaneous. Objectives: To verify the diagnostic and therapeutic recommendations in chronic spontaneous urticaria (CSU), according to the experience of Brazilian experts, r...

Data: 2019   |   Origem: Oasisbr

Correlation between the histopathology of chronic urticaria and its clinical pi...

Marques,Raquel Zappa Silva; Criado,Roberta Fachini Jardim; Machado Filho,Carlos D'Apparecida Santos; Tamanini,Juliana Milhomem

Abstract BACKGROUND: Chronic urticaria is characterized by transient, pruritic lesions of varying sizes, with central pallor and well-defined edges, with disease duration longer than six weeks. Its cellular infiltrate consists of neutrophils, lymphocytes and eosinophils. There is a subgroup of patients with eosinophilic or neutrophilic urticaria, resistant to the treatment with antihistamines, but that respond ...

Data: 2016   |   Origem: Oasisbr

Immunoelectron microscopy study of superficial skin nerves in drug-induced acut...

Criado,Paulo Ricardo; Criado,Roberta Fachini Jardim; Takakura,Cleusa F.H.; Pagliari,Carla; Sotto,Mirian Nacagami; Vasconcellos,Cidia

BACKGROUND: Few studies have evaluated the ultrastructure of the superficial skin nerves in urticaria. OBJECTIVE: The objective of this study was to describe findings in superficial skin nerves in cases of drug-induced acute urticaria. METHODS: Seven patients with drug-induced acute urticaria were included in the study. Skin biopsies were obtained from the urticarial lesion and from the apparently normal skin. ...

Data: 2012   |   Origem: Oasisbr

Drug reaction with Eosinophilia and Systemic Symptoms (DRESS) / Drug-induced Hy...

Criado,Paulo Ricardo; Criado,Roberta Fachini Jardim; Avancini,João de Magalhães; Santi,Claudia Giuli

The Drug Reaction with Eosinophilia and Systemic Symptoms syndrome, also known as Drug Induced Hypersensitivity Syndrome presents clinically as an extensive mucocutaneous rash, accompanied by fever, lymphadenopathy, hepatitis, hematologic abnormalities with eosinophilia and atypical lymphocytes, and may involve other organs with eosinophilic infiltration, causing damage to several systems, especially to the kid...

Data: 2012   |   Origem: Oasisbr

Cimidíase (dermatose por percevejo): uma causa de prurigo a ser lembrada

Criado,Paulo Ricardo; Criado,Roberta Fachini Jardim

Descrevemos uma doente de 19 anos que nos procurou com quadro de intenso prurido há 2 semanas e demonstrando lesões eritêmato-pápulo-urticadas mais intensamente distribuídas nos membros superiores e inferiores. A anamnese detalhada excluiu causas internas e medicamentos como uma possível causa do prurigo. Após orientações quanto a dedetização do domicílio a doente retornou no consultório após 3 semanas sem lesõ...

Data: 2011   |   Origem: Oasisbr

Bedbugs (Cimicidae infestation): the worldwide renaissance of an old partner of...

Criado,Paulo Ricardo; Belda Junior,Walter; Criado,Roberta Fachini Jardim; Silva,Roberta Vasconcelos e; Vasconcellos,Cidia

Bedbugs have been known as a human parasite for thousands of years, but scientific studies about this insect are recent and limited. Cimex lectularius, the common bedbug, was a well-known parasite in human dwellings until the end of the Second World War. Nowadays, bedbugs are considered uncommon in the industrialized world. Anecdotal reports suggest that bedbugs are getting more common in the United States, Can...

Data: 2011   |   Origem: Oasisbr

Histamina, receptores de histamina e anti-histamínicos: novos conceitos

Criado,Paulo Ricardo; Criado,Roberta Fachini Jardim; Maruta,Celina W.; Machado Filho,Carlos d'Apparecida

As drogas com ação anti-histamínica estão entre as medicações mais comumente prescritas na prática dermatológica diária, tanto em adultos como em crianças. Este artigo aborda os novos conceitos da função dos receptores de histamina (receptores H1) e discute os efeitos anti-inflamatórios dessas drogas. A segunda geração de anti-histamínicos difere da primeira geração devido a sua elevada especificidade e afinida...

Data: 2010   |   Origem: Oasisbr

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